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[在Plantival plus影响下的睡眠多导记录]

[Polygraphic recording of sleep under the influence of Plantival plus].

作者信息

Jovanović U J

出版信息

Fortschr Med. 1976 Mar 11;94(8):457-63.

PMID:9347
Abstract

10 patients with moderate non-psychotic sleep disturbances were investigated polygraphically for a total of 14 nights each. These 14 nights were subdivided into 4 test series: Placebo was given during the first, Plantival plus during the second and third and placebo again during the fourth series. The results showed that wakefulness decreased after the application of Plantival plus and that there was an increase in deep sleep. These effects could be observed mainly during the first hour of sleep and disappeared gradually during the later sleeping hours. REM-phases were not influenced by the medication. Due to these observations, Plantival plus should mainly be applicated when disturbances in falling asleep and problems in sleeping continuously occur. In case interrupted sleep in the early morning hours has been found, this preparation could be applicated only in combination with other kinds of treatment.

摘要

对10名患有中度非精神病性睡眠障碍的患者进行了多导睡眠图检查,每人共检查14个晚上。这14个晚上被分为4个测试系列:第一个系列给予安慰剂,第二个和第三个系列给予植物缬草加,第四个系列再次给予安慰剂。结果表明,服用植物缬草加后清醒时间减少,深度睡眠增加。这些效果主要在睡眠的第一个小时内观察到,并在随后的睡眠时间逐渐消失。快速眼动睡眠阶段不受药物影响。基于这些观察结果,植物缬草加主要应在入睡困难和持续睡眠问题出现时使用。如果发现清晨睡眠中断,这种制剂只能与其他治疗方法联合使用。

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