Spungen A M, Grimm D R, Lesser M, Bauman W A, Almenoff P L
Spinal Cord Damage Research Center, Veterans Affairs Medical Center, Bronx, NY 10468, USA.
Spinal Cord. 1997 Oct;35(10):652-7. doi: 10.1038/sj.sc.3100489.
To determine the prevalence of respiratory symptoms in subjects with chronic spinal cord injury (SCI), 180 subjects completed a standard respiratory questionnaire modified for subjects with limited mobility. Subjects were categorized as high tetraplegia (HT:C5 and above not requiring mechanical ventilation), low tetraplegia (LT: C6-8), high paraplegia (HP: T1-7), or low paraplegia (LP: T8-L3). Overall, 68% of subjects reported one or more respiratory symptom. Breathlessness, the most prevalent complaint, was associated with level of lesion: HT = 73%, LT = 58%, HP = 43% and LP = 29%, whereas complaints of cough, phlegm, cough and phlegm, and wheeze did not differ significantly among subjects in the four groups. Breathlessness occurred significantly more often in the group with HT during rest or following exposure to hot air or passive smoke. Awareness of phlegm or wheeze was reported with increased prevalence among subjects with tetraplegia who had complete injuries. Among subjects with tetraplegia, respiratory complaints did not differ significantly in current smokers, former smokers, and non-smokers, whereas among subjects with paraplegia, phlegm and wheeze were reported more frequently, among current smokers.
为确定慢性脊髓损伤（SCI）患者呼吸系统症状的患病率，180名患者完成了一份针对行动不便患者修改的标准呼吸问卷。患者被分为高位四肢瘫（HT：C5及以上且无需机械通气）、低位四肢瘫（LT：C6 - 8）、高位截瘫（HP：T1 - 7）或低位截瘫（LP：T8 - L3）。总体而言，68%的患者报告有一项或多项呼吸系统症状。呼吸急促是最常见的症状，与损伤平面相关：HT为73%，LT为58%，HP为43%，LP为29%，而咳嗽、咳痰、咳嗽伴咳痰以及喘息症状在四组患者中无显著差异。HT组在休息时或接触热空气或被动吸烟后呼吸急促的发生率明显更高。四肢瘫完全损伤患者对咳痰或喘息的知晓率有所增加。在四肢瘫患者中，目前吸烟者、既往吸烟者和非吸烟者的呼吸系统症状无显著差异，而在截瘫患者中，目前吸烟者咳痰和喘息的报告更为频繁。
