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交叉、交换与减数分裂染色体分离

Chiasmata, crossovers, and meiotic chromosome segregation.

作者信息

Bascom-Slack C A, Ross L O, Dawson D S

机构信息

Department of Microbiology and Molecular Biology, Tufts University, Boston, Massachusetts 02111, USA.

出版信息

Adv Genet. 1997;35:253-84. doi: 10.1016/s0065-2660(08)60452-6.

Abstract

Meiotic recombination events are probably critical for the completion of several meiotic processes. In addition, recombination is likely to be involved in the events that lead up to synapsis of homologues in meiotic prophase. Recombination events that ultimately become resolved as exchanges are needed for the formation of chiasmata. Chiasmata maintain the association of paired homologues following loss of the synaptonemal complex and participate in the mechanism that signals that the bivalent has attached to the spindle in a bipolar orientation that will result in meiosis I disjunction.

摘要

减数分裂重组事件可能对几个减数分裂过程的完成至关重要。此外,重组可能参与了减数分裂前期同源染色体联会之前的一系列事件。最终以交换形式得以解决的重组事件是形成交叉所必需的。交叉在联会复合体消失后维持配对同源染色体的关联,并参与一种机制,该机制表明二价体已以双极方向附着于纺锤体,这将导致减数第一次分裂分离。

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