Fried L P, McNamara R L, Burke G L, Siscovick D S
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
West J Med. 1997 Oct;167(4):240-6.
Coronary heart disease remains the leading cause of morbidity and mortality in older adults, despite improved survival and declining mortality. This article describes the prevalence and impact of heart disease on people's lives, singly and in combination with other diseases. It then reviews current findings as to the risk factors for CHD in older adults and the underlying physiologic changes of aging plus pathophysiologic changes of hypertension and CHD in impairing the ability of older adults to respond to exercise and other stressors, and the effects of exercise training in attenuating the adverse cardiovascular changes of aging. This information provides a basis for considering opportunities for prevention of heart disease and maximizing heart function. The article concludes by describing the known contribution of preventive measures to declines in heart disease in older adults.
尽管生存率有所提高且死亡率有所下降,但冠心病仍是老年人发病和死亡的主要原因。本文描述了心脏病单独或与其他疾病合并对人们生活的影响和患病率。然后回顾了关于老年人冠心病危险因素的当前研究结果,以及衰老的潜在生理变化、高血压和冠心病的病理生理变化如何损害老年人应对运动和其他应激源的能力,以及运动训练在减轻衰老引起的不良心血管变化方面的作用。这些信息为考虑预防心脏病的机会和最大化心脏功能提供了依据。本文最后描述了预防措施对老年人心脏病发病率下降的已知贡献。