耐糖肽屎肠球菌菌株在暴发期间可改变其万古霉素基因型。
Strains of glycopeptide-resistant Enterococcus faecium can alter their van genotypes during an outbreak.
作者信息
Woodford N, Chadwick P R, Morrison D, Cookson B D
机构信息
Laboratory of Hospital Infection, Central Public Health Laboratory, London, United Kingdom.
出版信息
J Clin Microbiol. 1997 Nov;35(11):2966-8. doi: 10.1128/jcm.35.11.2966-2968.1997.
Abstract
Two isolates of Enterococcus faecium with VanA glycopeptide resistance were isolated during a hospital outbreak of E. faecium with plasmid-mediated VanB resistance. Both were found to be identical to the VanB outbreak strain by pulsed-field gel electrophoresis. The genotype of this strain changed from vanB to vanA through an intermediate isolate that contained both the vanA and vanB gene clusters on distinct plasmids.
摘要
在医院爆发的由质粒介导的VanB耐药性屎肠球菌疫情期间，分离出了两株具有VanA糖肽耐药性的屎肠球菌。通过脉冲场凝胶电泳发现，这两株菌与VanB爆发菌株完全相同。该菌株的基因型通过一个中间分离株从vanB转变为vanA，该中间分离株在不同的质粒上同时含有vanA和vanB基因簇。
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