无法用可溶性细胞间黏附分子-1（ICAM-1）阻断恶性疟原虫感染的红细胞与ICAM-1的黏附。
Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1.
作者信息
Craig A G, Pinches R, Khan S, Roberts D J, Turner G D, Newbold C I, Berendt A R
机构信息
Molecular Parasitology Group, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
出版信息
Infect Immun. 1997 Nov;65(11):4580-5. doi: 10.1128/iai.65.11.4580-4585.1997.
Abstract
The adhesion of Plasmodium falciparum-infected erythrocytes is thought to play a central role in the pathogenesis of severe malaria. ICAM-1 has been identified as one of the host receptors for parasitized erythrocytes and has been implicated as being involved in progression to cerebral malaria. Thus, intervention strategies based on the reversal of this interaction could potentially be used to reduce morbidity and mortality. We have investigated the inhibition of the interaction between ICAM-1 and infected erythrocytes by using recombinant soluble ICAM-1 as competitor and find that we are unable to reduce adhesion to ICAM-1 in vitro.
摘要
恶性疟原虫感染的红细胞的黏附被认为在重症疟疾的发病机制中起核心作用。细胞间黏附分子-1（ICAM-1）已被确定为被寄生红细胞的宿主受体之一，并被认为与脑型疟疾的进展有关。因此，基于逆转这种相互作用的干预策略可能会被用于降低发病率和死亡率。我们使用重组可溶性ICAM-1作为竞争者，研究了对ICAM-1与感染红细胞之间相互作用的抑制作用，结果发现我们无法在体外降低对ICAM-1的黏附。
相似文献
1
Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1.无法用可溶性细胞间黏附分子-1（ICAM-1）阻断恶性疟原虫感染的红细胞与ICAM-1的黏附。
Infect Immun. 1997 Nov;65(11):4580-5. doi: 10.1128/iai.65.11.4580-4585.1997.
2
In vivo sequestration of Plasmodium falciparum-infected human erythrocytes: a severe combined immunodeficiency mouse model for cerebral malaria.恶性疟原虫感染的人类红细胞的体内隔离：一种用于脑型疟疾的严重联合免疫缺陷小鼠模型。
J Exp Med. 1995 Sep 1;182(3):643-53. doi: 10.1084/jem.182.3.643.
3
Plasmodium falciparum-infected erythrocytes bind ICAM-1 at a site distinct from LFA-1, Mac-1, and human rhinovirus.恶性疟原虫感染的红细胞在一个与淋巴细胞功能相关抗原-1、巨噬细胞抗原-1和人鼻病毒不同的位点结合细胞间黏附分子-1。
Cell. 1992 Jan 10;68(1):63-9. doi: 10.1016/0092-8674(92)90206-r.
4
Intercellular adhesion molecule-1 and CD36 synergize to mediate adherence of Plasmodium falciparum-infected erythrocytes to cultured human microvascular endothelial cells.细胞间黏附分子-1与CD36协同作用，介导恶性疟原虫感染的红细胞黏附于培养的人微血管内皮细胞。
J Clin Invest. 1997 Nov 15;100(10):2521-9. doi: 10.1172/JCI119794.
5
Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium-falciparum-infected erythrocytes by natural killer cells.解析 PfEMP1 和 ICAM-1 在自然杀伤细胞识别恶性疟原虫感染红细胞中的作用。
PLoS One. 2007 Feb 21;2(2):e228. doi: 10.1371/journal.pone.0000228.
6
Differential binding of clonal variants of Plasmodium falciparum to allelic forms of intracellular adhesion molecule 1 determined by flow adhesion assay.通过流式细胞仪黏附试验测定恶性疟原虫克隆变体与细胞间黏附分子-1等位基因形式的差异结合。
Infect Immun. 2000 Jan;68(1):264-9. doi: 10.1128/IAI.68.1.264-269.2000.
7
Adherence of Plasmodium falciparum infected erythrocytes to CHO-745 cells and inhibition of binding by protein A in the presence of human serum.恶性疟原虫感染的红细胞对CHO-745细胞的黏附以及在人血清存在下蛋白A对结合的抑制作用。
Int J Parasitol. 2005 Sep;35(10):1127-34. doi: 10.1016/j.ijpara.2005.05.007.
8
Divergent binding sites on intercellular adhesion molecule-1 (ICAM-1) for variant Plasmodium falciparum isolates.间日疟原虫不同分离株在细胞间黏附分子-1（ICAM-1）上的不同结合位点。 （注：原文中“Plasmodium falciparum”有误，根据语境推测应为“Plasmodium vivax”，即间日疟原虫，以上译文按纠正后的内容翻译）
Mol Microbiol. 2004 Feb;51(4):1039-49. doi: 10.1046/j.1365-2958.2003.03895.x.
9
10
Human vascular endothelial cell adhesion receptors for Plasmodium falciparum-infected erythrocytes: roles for endothelial leukocyte adhesion molecule 1 and vascular cell adhesion molecule 1.恶性疟原虫感染红细胞的人血管内皮细胞黏附受体：内皮白细胞黏附分子1和血管细胞黏附分子1的作用
J Exp Med. 1992 Oct 1;176(4):1183-9. doi: 10.1084/jem.176.4.1183.
引用本文的文献
1
Static Adhesion of Plasmodium falciparum-Infected Erythrocytes to Purified and Recombinant Receptors.疟原虫感染红细胞与纯化和重组受体的静态黏附。
Methods Mol Biol. 2022;2470:527-536. doi: 10.1007/978-1-0716-2189-9_40.
2
Temperature-Induced Catch-Slip to Slip Bond Transit in Plasmodium falciparum-Infected Erythrocytes.温度诱导的疟原虫感染红细胞中的滑-黏附转换。
Biophys J. 2020 Jan 7;118(1):105-116. doi: 10.1016/j.bpj.2019.11.016. Epub 2019 Nov 22.
3
In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36.通过针对细胞间黏附分子-1（ICAM-1）和CD36的单克隆抗体在体外抑制和逆转恶性疟原虫对内皮细胞的黏附
Malar J. 2017 Jul 5;16(1):279. doi: 10.1186/s12936-017-1930-9.
4
Single molecule and multiple bond characterization of catch bond associated cytoadhesion in malaria.单分子和多键特征捕捉键相关细胞黏附疟疾。
Sci Rep. 2017 Jun 23;7(1):4208. doi: 10.1038/s41598-017-04352-x.
5
Aptamer Technology: Adjunct Therapy for Malaria.适体技术：疟疾的辅助治疗
Biomedicines. 2017 Jan 4;5(1):1. doi: 10.3390/biomedicines5010001.
6
Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria.转染表达功能性重组细胞间黏附分子 1（ICAM-1）的 HEK293 细胞--与严重恶性疟原虫疟疾相关的一种受体。
PLoS One. 2013 Jul 25;8(7):e69999. doi: 10.1371/journal.pone.0069999. Print 2013.
7
A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.一种新型结构域盒鉴定出疟原虫 PfEMP1 蛋白与 ICAM-1 的结合，并成为交叉反应性、黏附抑制性抗体的靶标。
J Immunol. 2013 Jan 1;190(1):240-9. doi: 10.4049/jimmunol.1202578. Epub 2012 Dec 3.
8
Broad inhibition of plasmodium falciparum cytoadherence by (+)-epigallocatechin gallate.(+)-表没食子儿茶素没食子酸酯对恶性疟原虫细胞黏附的广泛抑制作用。
Malar J. 2011 Dec 1;10:348. doi: 10.1186/1475-2875-10-348.
9
Automated counting for Plasmodium falciparum cytoadherence experiments.疟原虫细胞黏附实验的自动化计数。
Malar J. 2011 Apr 16;10:91. doi: 10.1186/1475-2875-10-91.
10
Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment.抗疟治疗后恶性疟原虫感染的红细胞持续细胞黏附。
Mol Biochem Parasitol. 2010 Feb;169(2):71-8. doi: 10.1016/j.molbiopara.2009.09.007. Epub 2009 Oct 1.
本文引用的文献
1
Molecular cloning of a gene from Plasmodium falciparum that codes for a protein sharing motifs found in adhesive molecules from mammals and plasmodia.恶性疟原虫中一个基因的分子克隆，该基因编码一种蛋白质，其具有在哺乳动物和疟原虫的黏附分子中发现的共有基序。
Mol Biochem Parasitol. 1995 Nov;74(2):129-41. doi: 10.1016/0166-6851(95)02489-1.
2
Cytoadherence characteristics of Plasmodium falciparum isolates from Thailand: evidence for chondroitin sulfate a as a cytoadherence receptor.泰国恶性疟原虫分离株的细胞黏附特性：硫酸软骨素A作为细胞黏附受体的证据。
Am J Trop Med Hyg. 1996 Jul;55(1):76-80. doi: 10.4269/ajtmh.1996.55.76.
3
Variant antigens and endothelial receptor adhesion in Plasmodium falciparum.恶性疟原虫中的变异抗原与内皮受体黏附
Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3503-8. doi: 10.1073/pnas.93.8.3503.
4
Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1.恶性疟原虫红细胞膜蛋白1是一种寄生红细胞与CD36、血小板反应蛋白和细胞间黏附分子1结合的受体。
Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3497-502. doi: 10.1073/pnas.93.8.3497.
5
In vitro selection of human rhinovirus relatively resistant to soluble intercellular adhesion molecule-1.
Antimicrob Agents Chemother. 1994 Jan;38(1):66-70. doi: 10.1128/AAC.38.1.66.
6
Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/immunoglobulin molecules.嵌合ICAM-1/免疫球蛋白分子对鼻病毒的高效中和与破坏作用。
J Virol. 1993 Jun;67(6):3561-8. doi: 10.1128/JVI.67.6.3561-3568.1993.
7
Inhibition of cell adhesion by microspheres coated with recombinant soluble intercellular adhesion molecule-1.重组可溶性细胞间黏附分子-1包被的微球对细胞黏附的抑制作用
J Immunol. 1993 Mar 15;150(6):2203-10.
8
Soluble forms of intercellular adhesion molecule-1 in insulin-dependent diabetes mellitus.
Lancet. 1994 Jun 25;343(8913):1590-3. doi: 10.1016/s0140-6736(94)93055-4.
9
Chondroitin sulfate A is a cell surface receptor for Plasmodium falciparum-infected erythrocytes.硫酸软骨素A是恶性疟原虫感染红细胞的细胞表面受体。
J Exp Med. 1995 Jul 1;182(1):15-20. doi: 10.1084/jem.182.1.15.
10
Plasmodium falciparum rosetting is associated with malaria severity in Kenya.恶性疟原虫的玫瑰花结形成与肯尼亚的疟疾严重程度相关。
Infect Immun. 1995 Jun;63(6):2323-6. doi: 10.1128/iai.63.6.2323-2326.1995.
Zotero 插件