Rao P M, Rhea J T, Novelline R A, Mostafavi A A, Lawrason J N, McCabe C J
Department of Radiology, Massachusetts General Hospital, Boston 02114, USA.
AJR Am J Roentgenol. 1997 Nov;169(5):1275-80. doi: 10.2214/ajr.169.5.9353441.
Helical CT combined with contrast material administered by mouth and through the colon has been shown to be accurate for appendiceal imaging. This investigation was performed to determine if helical CT combined with contrast material administered only through the colon has comparable accuracy.
One hundred patients prospectively underwent appendiceal CT imaging with thin-collimation, helical scanning limited to the lower abdomen and upper pelvis after contrast material was administered only through the colon. CT results were correlated with surgical and pathologic findings at appendectomy (56 patients), other surgery (three patients), or clinical follow-up at least 2 months after the CT scan (41 patients).
Fifty-three CT scans were interpreted as positive for appendicitis, including 52 true-positives (with surgical-pathologic correlation) and on false-positive (with clinical follow-up). Forty-seven CT scans were interpreted as negative for appendicitis, including 40 true-negatives with clinical follow-up, three true-negatives with appendectomy and pathologic correlation, three true-negatives with other surgery and pathologic correlation, and one false-negative with appendectomy and pathologic correlation. CT had a 98% sensitivity, 98% specificity, 98% positive predictive value, 98% negative predictive value, and 98% accuracy for diagnosing or excluding appendicitis. In 47 normal appendix cases at CT, the appendix was seen in 44 cases (94%), and an alternative diagnosis was identified in 29 cases (62%).
For diagnosing appendicitis, helical CT combined with contrast material administered only through the colon proved to be as accurate (98%) as helical CT combined with contrast material administered by mouth and through the colon. Helical CT with contrast material administered only through the colon also could be performed immediately and without any of the potential patient risks or discomforts of contrast material administered i.v. or by mouth.
螺旋CT联合经口服及经结肠注入对比剂已被证明对阑尾成像准确。本研究旨在确定螺旋CT仅联合经结肠注入对比剂是否具有同样的准确性。
100例患者仅经结肠注入对比剂后,接受了针对阑尾的薄层准直螺旋CT扫描,扫描范围限于下腹部和上骨盆。CT结果与阑尾切除术中的手术及病理结果(56例患者)、其他手术(3例患者)或CT扫描后至少2个月的临床随访结果(41例患者)进行了对比。
53例CT扫描被解读为阑尾炎阳性,包括52例假阳性(与手术病理结果相关)和1例假阳性(与临床随访结果相关)。47例CT扫描被解读为阑尾炎阴性,包括40例经临床随访的真阴性、3例经阑尾切除及病理相关的真阴性、3例经其他手术及病理相关的真阴性以及1例经阑尾切除及病理相关的假阴性。CT诊断或排除阑尾炎的敏感性为98%,特异性为98%,阳性预测值为98%,阴性预测值为98%,准确性为98%。在CT显示阑尾正常的47例病例中,44例(94%)可见阑尾,29例(62%)发现了其他诊断结果。
对于诊断阑尾炎,仅经结肠注入对比剂的螺旋CT被证明与联合经口服及经结肠注入对比剂的螺旋CT一样准确(98%)。仅经结肠注入对比剂的螺旋CT还可立即进行,且不存在静脉注射或口服对比剂所带来的任何潜在患者风险或不适。