混合脂质体对HL-60细胞生长具有显著抑制作用，并伴有凋亡诱导作用。
Remarkable inhibitory effects of hybrid liposomes on the growth of HL-60 cells coupled to induction of apoptosis.
作者信息
Imamura C, Kemura Y, Matsumoto Y, Ueoka R
机构信息
Kumamoto Institute of Technology, Japan.
出版信息
Biol Pharm Bull. 1997 Oct;20(10):1119-21. doi: 10.1248/bpb.20.1119.
PMID:9353577
Abstract
The hybrid liposomes (90 mol% DMPC/10 mol% C12(EO)10 or C12(EO)12) have a highly inhibitory effect on the growth of tumor cells (HL-60). The induction of apoptosis by the hybrid liposomes in HL-60 cells was revealed on the basis of flow cytometry and DNA electrophoresis.
摘要
混合脂质体（90摩尔％二肉豆蔻酰磷脂酰胆碱/10摩尔％C12(EO)10或C12(EO)12）对肿瘤细胞（HL-60）的生长具有高度抑制作用。基于流式细胞术和DNA电泳揭示了混合脂质体在HL-60细胞中诱导凋亡的现象。
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