Higgins C B, Wexler L, Silverman J F, Hayden W G, Anderson W L, Schroeder J H
Radiology. 1976 Jun;119(3):521-7. doi: 10.1148/119.3.521.
Eleven of 21 consecutive patients with Prinzmetal angina (PMA) exhibited no significant fixed stenoses of the coronary arteries. Spontaneous coronary arterial spasm was demonstrated in 3 patients. Ergonovine maleate produced near-total occlusion of a major vessel in 3 of 4 other patients with PMA, but did not provoke spasm in 10 without PMA. The current study documents spasm as the mechanism of myocardial ischemia in some patients with normal coronary arteries and provides initial and favorable diagnostic results with provocative pharmacoangiography in this entity.
21例连续性变异型心绞痛（PMA）患者中，11例冠状动脉无明显固定狭窄。3例患者出现自发性冠状动脉痉挛。在另外4例PMA患者中，3例静脉注射马来酸麦角新碱后出现主要血管近乎完全闭塞，但在10例非PMA患者中未诱发痉挛。本研究证明痉挛是一些冠状动脉正常患者心肌缺血的机制，并在此类患者中通过激发性药物血管造影提供了初步且良好的诊断结果。
