成功治疗后患有霍奇金病的儿童出现复发性纵隔肿块：一项诊断挑战。
Recurrent mediastinal mass in a child with Hodgkin's disease following successful therapy: a diagnostic challenge.
作者信息
Feldges A, Wagner H P, Bubeck B, Kehrer B, Ries G, Schmid U, Waibel P
机构信息
Ostschweizerisches Kinderspital, CH-9006 St. Gallen, Switzerland.
出版信息
Pediatr Surg Int. 1997;12(8):613-7. doi: 10.1007/BF01371913.
The case of an 11-year-old girl with mediastinal stage III B-E Hodgkin's disease is described. She achieved complete remission with combined chemoradiotherapy according to the Swiss Pediatric Oncology Group-HD Protocol 1985. Six months after all therapy was stopped, a slowly growing retrosternal mass was detected. Computed tomography (CT) and gallium-67 single-photon emission CT (SPECT) could not elucidate the true origin of the tumor, nor did ultrasound-guided transthoracic fine-needle puncture. Open biopsy with histologic examination of the lesion has successfully identified the mass as thymic hyperplasia, a rebound immunologic reaction after chemoradiotherapy that mimicked tumor regrowth.
本文描述了一名11岁患有纵隔III B - E期霍奇金病的女孩的病例。根据1985年瑞士儿科肿瘤学组 - 霍奇金病方案，她通过放化疗联合治疗实现了完全缓解。在所有治疗停止6个月后，发现一个胸骨后肿物生长缓慢。计算机断层扫描（CT）和镓 - 67单光子发射CT（SPECT）均无法明确肿瘤的真正起源，超声引导下经胸细针穿刺也未能明确。对病变进行开放活检及组织学检查成功将肿物鉴定为胸腺增生，这是放化疗后的一种免疫反应反弹，类似于肿瘤复发。
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