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老年人的慢性炎症:识别、后果及潜在干预措施

Chronic inflammation in older people: recognition, consequences, and potential intervention.

作者信息

Ballou S P, Kushner I

机构信息

Division of Rheumatology, Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA.

出版信息

Clin Geriatr Med. 1997 Nov;13(4):653-69.

PMID:9354747
Abstract

In elderly individuals, some chronic inflammatory diseases appear to occur with increased frequency, and recent evidence suggests that some very common chronic, age-related disorders may be propagated and perpetuated by inflammatory processes, perhaps giving rise to the abnormal acute phase protein levels that are seen with increased frequency with aging. The consequences of chronic inflammation in the elderly undoubtedly contribute to excessive morbidity in this population. Treatment of chronic inflammation in the elderly is often difficult, requiring utmost care and close follow-up by a knowledgeable and dedicated physician.

摘要

在老年人中,一些慢性炎症性疾病的发生频率似乎有所增加,最近的证据表明,一些非常常见的慢性、与年龄相关的疾病可能由炎症过程引发并持续存在,这或许导致了随着年龄增长而频繁出现的异常急性期蛋白水平。老年人慢性炎症的后果无疑导致了该人群中过高的发病率。治疗老年人的慢性炎症往往很困难,需要知识渊博且专注的医生给予 utmost care 和密切随访。 (注:“utmost care”可能有误,推测可能是“utmost caution”,但按要求未做修改)

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