Arai Y, Ishitoya S, Okubo K, Aoki Y, Okada T, Maeda H, Suzuki Y
Department of Urology, Kurashiki Central Hospital, Japan.
Int J Urol. 1997 Sep;4(5):487-92. doi: 10.1111/j.1442-2042.1997.tb00291.x.
Nerve-sparing techniques are used during retroperitoneal lymph node dissection (RPLND) in patients with early stage testicular cancer to preserve postoperative ejaculatory function. Indications for the procedures have been extended to patients with a postchemotherapy retroperitoneal residual mass without compromising the efficacy of surgery. We report 6 cases diagnosed with metastatic testicular cancer who underwent nerve-sparing RPLND.
Between January 1994 and March 1996, 6 patients with metastatic testicular cancer underwent nerve-sparing RPLND. Five of these patients received primary chemotherapy and a retroperitoneal residual mass. Four patients underwent complete bilateral RPLND and 2 underwent unilateral template surgery.
After a mean follow-up of 18.7 months (range, 8 to 34), there have been no local recurrences and 5 (83%) patients report antegrade ejaculation.
Nerve-sparing RPLND is applicable for selected patients with metastatic testicular cancer without increasing the risk of local recurrence. Ejaculatory function is preserved in the majority of patients, contributing to the improvement of the quality of life in men who require such surgery.
在早期睾丸癌患者的腹膜后淋巴结清扫术(RPLND)中采用保留神经技术以保留术后射精功能。该手术的适应证已扩展至化疗后腹膜后残留肿块的患者,且不影响手术疗效。我们报告6例诊断为转移性睾丸癌并接受保留神经RPLND的病例。
1994年1月至1996年3月,6例转移性睾丸癌患者接受了保留神经RPLND。其中5例患者接受了一线化疗并有腹膜后残留肿块。4例患者接受了双侧完整RPLND,2例接受了单侧模板手术。
平均随访18.7个月(范围8至34个月)后,无局部复发,5例(83%)患者报告有顺行射精。
保留神经RPLND适用于部分转移性睾丸癌患者,且不增加局部复发风险。大多数患者的射精功能得以保留,有助于改善需要此类手术的男性的生活质量。