Fu K K, Phillips T L
Radiology. 1976 Aug;120(2):439-41. doi: 10.1148/120.2.439.
EMT6 tumors were exposed to neon ions in vivo and in vitro in the plateau and spread-out Bragg peak regions of the beam. The RBE in vivo was 1.7-2.1 in the plateau region and 2.6-2.9 in the Bragg peak; the OER was 2.0 and 1.4, respectively. Neon ions have great potential in the radiotherapy of tumors because of their decreased OER and excellent depth-dose distribution in tissue.
EMT6肿瘤在体内和体外接受了位于束流的坪区和扩展布拉格峰区的氖离子照射。体内坪区的相对生物效应(RBE)为1.7 - 2.1,布拉格峰区为2.6 - 2.9;氧增强比(OER)分别为2.0和1.4。由于氖离子降低的OER以及在组织中优异的深度剂量分布,其在肿瘤放射治疗中具有巨大潜力。