Suzuki K, Nishiyama N, Nemoto K, Asakura T, Nakai H
Department of Dental Materials, Okayama University, Dental School, Japan.
J Biomed Mater Res. 1997 Nov;37(2):261-6. doi: 10.1002/(sici)1097-4636(199711)37:2<261::aid-jbm16>3.0.co;2-h.
To ascertain the adhesion mechanism of resins to etched dentin treated with hydrophilic primers such as N-methacryloyl-omega-amino acids (NM omega A), the effect of the application of NM omega A primers on the bond strength of the resin and also the characteristics of the "hybrid layer" were investigated. Here, the concept of "hybrid layer" has been proposed previously by Nakabayashi et al. When the demineralized dentin was treated with the NM omega A solution, the bond strength increased remarkably, thus indicating the formation of a hybrid layer. It can be construed that NM omega A primers allowed for diffusion of the bonding agent to the dentinal collageous layer that was exposed by acid etching, and thereby the creation of a hybrid layer. To obtain an understanding of how NM omega A primers improved bond strength at the interface between the resin and dentinal collagen, the 13C-NMR spectra of NM alpha A were observed in the absence and presence of demineralized dentin. The 13C peak intensities of all of the carbons of the NM alpha A species were dramatically reduced in the presence of the dentin. Specifically, the reduction of the carbon peak intensity of carboxylic acid in the NM alpha A species was reduced by 30%. This indicated that the unionized carboxylic acid in the NM alpha A primer interacted with the dentinal collagen. Thus, the composite resin can be considered to adhere to the dentinal collagen through the unionized NM alpha A that interacts with the dentinal collagen.
为了确定树脂与经亲水性底漆（如N-甲基丙烯酰基-ω-氨基酸，NMωA）处理的酸蚀牙本质之间的黏附机制，研究了NMωA底漆的应用对树脂粘结强度的影响以及“混合层”的特性。在此，“混合层”的概念先前已由中林等人提出。当用NMωA溶液处理脱矿牙本质时，粘结强度显著提高，这表明形成了混合层。可以推断，NMωA底漆使粘结剂扩散到酸蚀暴露的牙本质胶原层，从而形成混合层。为了了解NMωA底漆如何提高树脂与牙本质胶原界面的粘结强度，在有无脱矿牙本质的情况下观察了NMαA的13C-NMR光谱。在有牙本质存在的情况下，NMαA所有碳的13C峰强度均显著降低。具体而言，NMαA中羧酸的碳峰强度降低了30%。这表明NMαA底漆中未电离的羧酸与牙本质胶原相互作用。因此，可以认为复合树脂通过与牙本质胶原相互作用的未电离NMαA与牙本质胶原黏附。
