König G M, Wright A D
Department of Pharmaceutical Biology, Technical University of Braunschweig, Germany.
J Nat Prod. 1997 Oct;60(10):967-70. doi: 10.1021/np970181r.
From the CH2Cl2 extract of the temperate marine red alga, Laurencia rigida, which has antifouling properties, eight sesquiterpenes (1-8) were isolated. Of these, four (3-acetoxy-E-gamma-bisabolene (1), (-)-10 alpha-bromo-9 beta-hydroxy-alpha-chamigrene (2), rigidol (3), and (+)-(10S)-10-bromo-beta-chamigrene (4)), were shown to be new natural products. For the known compound deschloroelatol (5), reassignment of the 1H- and 13C-NMR data was found to be necessary on the basis of extensive NMR measurements. For elatol (6), complete 1H- and 13C-NMR data are also reported. The antimicrobial and antialgal activities of all isolates were assessed.
从具有防污性能的温带海洋红藻硬叶劳伦氏藻的二氯甲烷提取物中，分离出了8种倍半萜（1 - 8）。其中，有4种（3 - 乙酰氧基 - E - γ - 红没药烯（1）、（ - ） - 10α - 溴 - 9β - 羟基 - α - 菖蒲烯（2）、硬叶醇（3）和（ + ） - （10S） - 10 - 溴 - β - 菖蒲烯（4））被证明是新的天然产物。对于已知化合物去氯埃拉托醇（5），基于广泛的核磁共振测量，发现有必要重新指定其1H - 和13C - NMR数据。对于埃拉托醇（6），也报道了完整的1H - 和13C - NMR数据。对所有分离物的抗菌和抗藻活性进行了评估。
