Sharmin F, Khan B R, Rahman M, Rashid H U, Islam B, Kamal M, Barua A R, Chowdhury M A, Mohsin A U, Ahmed S
Department of Pathology, Dhaka Medical College.
Bangladesh Med Res Counc Bull. 1997 Apr;23(1):25-9.
A light and immunofluorescence microscopic study on renal biopsies were performed on 42 patients. Nephrotic syndrome with accompanying microhematuria and recurrent hematuria (Macroscopic/microscopic) with or without renal failure were the commonest indications for renal biopsy. Primary IgA nephropathy was diagnosed in five cases. Among the IgA nephropathy patients, the commonest light microscopic finding was mesangial proliferative glomerulonephritis. Macroscopic hematuria with proteinuria was the commonest feature. Three of the patients had hypertension at the time of renal biopsy. The age of the patients ranged from 19-38 years with a mean of 26 years. The high frequency of hypertension, degree of proteinuria and associated renal failure in one patient that it is a progressive disease. This preliminary study revealed that IgA nephropathy exists in Bangladesh. Larger samples need to be studied with a view to find out its prevalence and its peculiarities in this part of the world.
对42例患者的肾活检组织进行了光镜和免疫荧光显微镜研究。肾病综合征伴镜下血尿以及复发性血尿（肉眼/镜下）伴或不伴肾衰竭是肾活检最常见的指征。5例患者被诊断为原发性IgA肾病。在IgA肾病患者中，最常见的光镜表现是系膜增生性肾小球肾炎。肉眼血尿伴蛋白尿是最常见的特征。3例患者在肾活检时患有高血压。患者年龄在19至38岁之间，平均年龄为26岁。高血压的高发生率、蛋白尿程度以及1例患者伴有肾衰竭表明它是一种进行性疾病。这项初步研究表明，孟加拉国存在IgA肾病。需要研究更大的样本，以查明其在世界这一地区的患病率及其特点。
