Deren S, Kotranski L, Beardsley M, Collier K, Tortu S, Semaan S, Lauby J, Hamid R
National Development and Research Institutes, Inc. New York, New York, USA.
Am J Drug Alcohol Abuse. 1997 Nov;23(4):555-67. doi: 10.3109/00952999709016895.
Crack use has been associated with increased risk for HIV seropositivity. This study was undertaken to examine HIV-related risk behaviors among crack users in East Harlem, New York and Philadelphia, Pennsylvania, two northeastern communities which have reported extensive crack use. Crack users recruited in East Harlem (n = 1434) and Philadelphia (n = 694) were compared on demographics, drug and sex-related risk behaviors, health-related behaviors, and HIV serostatus. Many significant differences were found, and seropositivity was higher in the New York sample (25% vs. 11%, chi 2 = 36.28, p < .001). Being a recent drug injector was a significant predictors of seropositivity in both communities, and differences between communities were found in additional predictors of serostatus. Results suggest that tailored HIV interventions may be needed for different communities. In addition, aggregate data across communities, even those that may be in geographical proximity, may obfuscate differences important to incorporate in developing prevention/intervention efforts.
吸食强效纯可卡因与艾滋病毒血清阳性风险增加有关。本研究旨在调查纽约市东哈莱姆区和宾夕法尼亚州费城这两个东北部社区中吸食强效纯可卡因者的艾滋病毒相关风险行为，这两个社区报告称存在广泛的强效纯可卡因吸食情况。对在东哈莱姆区招募的1434名强效纯可卡因吸食者和在费城招募的694名强效纯可卡因吸食者的人口统计学特征、与毒品和性相关的风险行为、与健康相关的行为以及艾滋病毒血清学状态进行了比较。发现了许多显著差异，纽约样本中的血清阳性率更高（25%对11%，卡方 = 36.28，p < 0.001）。近期注射毒品是两个社区血清阳性的重要预测因素，并且在血清学状态的其他预测因素方面发现了社区之间的差异。结果表明，可能需要针对不同社区量身定制艾滋病毒干预措施。此外，跨社区的汇总数据，即使是那些地理位置相近的社区，也可能掩盖对于制定预防/干预措施至关重要的差异。
