Koonin E V
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, USA.
Curr Biol. 1997 Oct 1;7(10):R656-9. doi: 10.1016/s0960-9822(06)00328-9.
The complete Escherichia coli genome sequence is now known; it should greatly facilitate the analysis of other genomes, but a lot remains to be learnt about E. coli itself. About half the genes were previously uncharacterized, but expanding databases and improving analysis methods will help predict their functions.
现在已知了完整的大肠杆菌基因组序列;这应该会极大地促进对其他基因组的分析,但关于大肠杆菌本身仍有许多有待了解的地方。以前约有一半的基因未被表征,但不断扩展的数据库和改进的分析方法将有助于预测它们的功能。