Akpek E K, Merchant A, Pinar V, Foster C S
Department of Immunology, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
Ophthalmology. 1997 Nov;104(11):1863-7.
The purpose of this report is to review the presenting symptoms and signs, treatment regimens used, complications encountered, and outcome in a cohort of patients with ocular rosacea.
The medical records of 131 patients with a diagnosis of ocular rosacea were reviewed retrospectively. Data were entered in a tabulated form, and a descriptive analysis was performed.
The age range at presentation was between 23 and 85 years (mean, 56 years). Cutaneous manifestations of rosacea were present in 112 of the patients at their first visit. The most common presenting symptoms were foreign body sensation and burning, and the most common signs were telangiectasia and irregularity of lid margins, and meibomian gland dysfunction. Thirteen patients had decreased visual acuity at the time of presentation due to corneal complications. Six of these patients required penetrating keratoplasty during the course of their disease. Seven patients had severe cicatrizing conjunctivitis at the time of referral. One hundred thirteen patients were treated with oral tetracycline derivatives. Seven patients were left with visual acuity less than 20/400, and one patient underwent enucleation for corneal perforation and endophthalmitis.
Ocular rosacea is a common disease involving the skin and the eyes. It is widely underdiagnosed by many ophthalmologists despite the blinding potential. Successful therapy requires a multidisciplinary approach.
本报告旨在回顾一组眼部酒渣鼻患者的症状和体征、所采用的治疗方案、所遇到的并发症及预后情况。
回顾性分析131例诊断为眼部酒渣鼻患者的病历。数据以表格形式录入,并进行描述性分析。
就诊时年龄范围为23至85岁(平均56岁)。112例患者初诊时伴有酒渣鼻的皮肤表现。最常见的症状是异物感和烧灼感,最常见的体征是毛细血管扩张、睑缘不规则和睑板腺功能障碍。13例患者就诊时因角膜并发症导致视力下降。其中6例患者在病程中需要进行穿透性角膜移植术。7例患者转诊时患有严重的瘢痕性结膜炎。113例患者接受口服四环素衍生物治疗。7例患者视力低于20/400,1例患者因角膜穿孔和眼内炎而接受眼球摘除术。
眼部酒渣鼻是一种累及皮肤和眼睛的常见疾病。尽管有致盲风险,但许多眼科医生对其诊断不足。成功的治疗需要多学科方法。