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妊娠晚期及产褥期的胰高血糖素分泌。

Glucagon secretion in late pregnancy and the puerperium.

作者信息

Leblanc H, Anderson J R, Yen S S

出版信息

Am J Obstet Gynecol. 1976 Jul 1;125(5):708-10. doi: 10.1016/0002-9378(76)90799-7.

DOI:10.1016/0002-9378(76)90799-7
PMID:937396
Abstract

Fasting plasma glucagon levels in late pregnancy were not significantly changed from those of nonpregnant matched control subjects, but at 6 to 8 weeks post partum a significant decrease in fasting glucagon levels was observed. Acute elevation of plasma glucose levels (via 25 Gm. intravenous glucose loading) induced a suppression of glucagon levels. This glucose-mediated glucagon suppression appeared to be less during late pregnancy which is probably related to the smaller increments of plasma glucose following intravenous loading in late pregnancy as compared to postpartum values.

摘要

妊娠晚期空腹血浆胰高血糖素水平与非妊娠匹配对照组相比无显著变化,但在产后6至8周,空腹胰高血糖素水平显著下降。血浆葡萄糖水平的急性升高(通过静脉注射25克葡萄糖负荷)可诱导胰高血糖素水平的抑制。这种葡萄糖介导的胰高血糖素抑制在妊娠晚期似乎较弱,这可能与妊娠晚期静脉注射负荷后血浆葡萄糖的增量较产后值小有关。

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引用本文的文献

1
A study on the hyperinsulinism of late pregnancy.晚期妊娠高胰岛素血症的研究。
J Endocrinol Invest. 1991 Nov;14(10):807-14. doi: 10.1007/BF03347933.