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The importance of oxidative stress in apoptosis.

作者信息

Clutton S

机构信息

MRC Radiation and Genome Stability Unit, Harwell, UK.

出版信息

Br Med Bull. 1997;53(3):662-8. doi: 10.1093/oxfordjournals.bmb.a011637.

DOI:10.1093/oxfordjournals.bmb.a011637
PMID:9374044
Abstract

In vitro studies have shown that apoptosis can be triggered by many distinct and different stimuli including exposure to physical and chemical agents or by the removal of growth factors. Free radicals and oxidative stress have been implicated in apoptosis, although there is much uncertainty regarding their importance. This review aims to address much of the existing ambiguity.

摘要

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