Serum lysozyme in sarcoid uveitis.

In a study of 100 patients, the mean serum lysozyme value for patients with sarcoidosis and active uveitis was elevated, while the mean value for patients with inactive sarcoidosis and inactive uveitis was within the normal range. The mean value for patients with a clinical picture of sarcoid uveitis, but without an established diagnosis of sarcoidosis, was high. In patients with ophthalmologic findings compatible with sarcoidosis, but without radiologic, immunologic, or other clinical evidence of the disease, an elevated serum lysozyme level may be indicative of sytemic disease.