Maddrey A M, Cullum C M, Weiner M F, Filley C M
University of Texas Southwestern Medical Center, Dallas 75235, USA.
J Int Neuropsychol Soc. 1996 Nov;2(6):551-5. doi: 10.1017/s1355617700001727.
Simple sight-word reading tasks have demonstrated utility in the estimation of premorbid intelligence, although the effects of progressive dementia on such tasks has not been thoroughly examined. The present investigation sought to examine estimated IQ scores from the National Adult Reading Test-Revised (NART-R; Blair & Spreen, 1989) in relation to a WAIS-R-based (Wechsler, 1981) estimate of IQ in a series of patients with probable Alzheimer's disease across varying levels of dementia. Results suggest that while NART-R scores do show a decrement with dementia severity, this decline is mild, in contrast to traditionally based IQ scores and other measures of cognitive function, which show more marked declines. Similarly, compared with other tasks, the NART-R showed the strongest correlation with education across the sample as a whole, while the other indices were more related to level of dementia. These findings support the use of measures such as the NART-R in estimating premorbid intellectual functioning in patients at various levels of dementia severity, including those with more advanced cognitive deterioration.
简单的视觉词汇阅读任务已被证明在病前智力评估中具有实用性，尽管进行性痴呆对此类任务的影响尚未得到充分研究。本研究旨在考察一系列不同痴呆程度的可能患有阿尔茨海默病的患者中，根据修订版国家成人阅读测验（NART-R；布莱尔和斯普林，1989）得出的估计智商分数与基于韦氏成人智力量表修订版（WAIS-R；韦克斯勒，1981）的智商估计值之间的关系。结果表明，虽然NART-R分数确实会随着痴呆严重程度的增加而下降，但这种下降较为轻微，这与传统的智商分数和其他认知功能测量指标形成对比，后者显示出更明显的下降。同样，与其他任务相比，NART-R在整个样本中与教育程度的相关性最强，而其他指标与痴呆程度的相关性更强。这些发现支持在评估不同痴呆严重程度患者（包括认知功能恶化更严重的患者）的病前智力功能时使用NART-R等测量方法。
