Department of Psychiatry, University of California, San Diego, 220 Dickinson Drive, St B (8231), San Diego, CA, 92103-8231, USA.
VA San Diego Healthcare System, San Diego, CA, USA.
AIDS Behav. 2018 Oct;22(10):3214-3225. doi: 10.1007/s10461-018-2061-1.
Grit and ambition are psychological factors that may protect neurocognitive function among persons living with HIV (PLWH). We examined associations between grit, ambition, premorbid verbal intellectual function, and current neurocognitive and everyday functioning among PLWH and persons without HIV (HIV-). 120 PLWH and 94 HIV- adults completed the Grit Scale (includes total score and consistency of interests and perseverance of effort subscales), ambition scale, and a comprehensive neurobehavioral battery. PLWH had lower grit scores than HIV- adults. The two groups did not differ on ambition. No relationship was observed between grit and cognition among HIV- adults. Among PLWH, however, higher perseverance of effort and more ambition was related to better global neurocognitive functioning, and higher grit, but not ambition, was related to independence in daily functioning. Longitudinal studies are needed to elucidate these relationships over time and examine whether grit or ambition have protective effects on cognitive outcomes among PLWH.
坚毅和野心是可能保护 HIV 感染者（PLWH）神经认知功能的心理因素。我们研究了 PLWH 和无 HIV 感染者（HIV-）个体之间的坚毅、野心、发病前言语智力功能以及当前神经认知和日常功能之间的关系。120 名 PLWH 和 94 名 HIV-成年人完成了坚毅量表（包括总分和兴趣一致性以及努力坚持分量表）、野心量表和全面的神经行为测试。PLWH 的坚毅得分低于 HIV-成年人。两组在野心方面没有差异。在 HIV-成年人中，坚毅与认知之间没有关系。然而，在 PLWH 中，更高的努力坚持和更大的野心与更好的整体神经认知功能相关，而更高的坚毅但不是野心与日常生活功能的独立性相关。需要进行纵向研究来阐明这些关系随时间的变化，并研究坚毅或野心是否对 PLWH 的认知结果具有保护作用。
