Cruz J M, Pato M, Gómez X A, Batalla A, Cutrin C
Servicio de Medicina Interna, Complejo Hospitalario Cristal-Piñor, Orense.
An Med Interna. 1997 Aug;14(8):415-8.
The neuroleptic malignant syndrome is a fulminant, life-threatening reaction to neuroleptic medication. It is characterized by fever, rigidity, autonomic disfunction and fluctuating consciousness. Usually described in young adults with psychiatry illnesses, its presentation in an elderly population has received scant attention in medical literature. We describe the clinics and evolutive characteristics of 4 cases of this syndrome in elderly which a mean age of 78 years. We emphasise about the existence of a brain organic illness with dementia as a predisposing factor, and the correct evolution of the showed cases in probably relation with measures and drug therapy.
神经阻滞剂恶性综合征是一种对神经阻滞剂药物的暴发性、危及生命的反应。其特征为发热、强直、自主神经功能障碍和意识波动。通常在患有精神疾病的年轻人中描述，其在老年人群中的表现在医学文献中很少受到关注。我们描述了4例平均年龄为78岁的老年患者该综合征的临床及演变特征。我们强调存在脑器质性疾病伴痴呆作为一个易感因素，以及所展示病例的正确演变可能与措施和药物治疗有关。
