Lintern-Moore S, Moore G P, Tyndale-Biscoe C H, Poole W E
Anat Rec. 1976 Jul;185(3):325-32. doi: 10.1002/ar.1091850306.
Oocyte growth in relation to follicular growth in marsupials conforms to the uniform biphasic pattern characteristic of eutherian mammals. However, the oocyte of the marsupial is larger and completes growth in a correspondingly larger follicle. At the completion of oocyte growth the follicle, like that of eutherians, shows no appreciable accumulation of follicular fluid. The ratio of oocyte/follicular diameter in marsupials at this stage is 0.59, a value close to that of 0.55 for eutherian mammals. The oocyte nucleus of the marsupial is also significantly larger than that of the eutherian, but the oocyte nucleolus is approximately the same diameter. By contrast, the growth of the oocyte in relation to the follicle in monotremes in linear throughout the whole period of follicular growth. However, like eutherians and marsupials oocyte nuclear and oocyte nucleolar growth are arrested in the early stages of follicular growth. The diameters of the oocyte nucleus and nucleolus at the completion of growth are approximately twice those found in marsupials. It is concluded that the growth patterns of the oocyte nucleus and nucleolus are common to all mammals but that the biphasic pattern of oocyte and follicular growth which is characteristic of eutherian and marsupial ovaries is not found in the monotremes.
有袋类动物的卵母细胞生长与卵泡生长的关系符合真兽类哺乳动物特有的统一双相模式。然而，有袋类动物的卵母细胞更大，并且在相应更大的卵泡中完成生长。在卵母细胞生长完成时，卵泡与真兽类动物的卵泡一样，没有明显的卵泡液积聚。在此阶段，有袋类动物卵母细胞/卵泡直径的比值为0.59，这一数值与真兽类哺乳动物的0.55相近。有袋类动物的卵母细胞核也明显大于真兽类动物的，但卵母细胞的核仁直径大致相同。相比之下，单孔类动物的卵母细胞在整个卵泡生长期间与卵泡的生长呈线性关系。然而，与真兽类动物和有袋类动物一样，卵母细胞核和卵母细胞的核仁生长在卵泡生长的早期阶段就停止了。生长完成时，卵母细胞核和核仁的直径大约是有袋类动物的两倍。得出的结论是，卵母细胞核和核仁的生长模式在所有哺乳动物中都很常见，但真兽类动物和有袋类动物卵巢特有的卵母细胞和卵泡生长的双相模式在单孔类动物中未发现。
