Nicolle L E
Department of Internal Medicine, University of Manitoba, St. Boniface Hospital, Winnipeg, Canada.
Infect Dis Clin North Am. 1997 Sep;11(3):647-62. doi: 10.1016/s0891-5520(05)70378-0.
Asymptomatic bacteriuria is frequent in elderly, populations. The major contributing factors are selected physiologic aging changes and comorbid illnesses, which occur with increased frequency in these populations. There is little short-term or long-term adverse outcomes attributable to this high prevalence and incidence of asymptomatic bacteriuria and no evidence for an impact on survival. A number of important questions relating to this problem have yet to be resolved. First, further studies in the noninstitutionalized population are needed to characterize the incidence of asymptomatic infection and its relationship to symptomatic infection. In the institutionalized population, studies to refine the clinical diagnosis of symptomatic urinary infection occurring in a population with such a high prevalence of asymptomatic bacteriuria are needed. In addition, further assessment of the impact of the reservoir of asymptomatic bacteriuria in elderly institutionalized subjects as a contributor to the problem of antimicrobial resistance in the institutionalized population should be a priority.
无症状菌尿在老年人群中很常见。主要促成因素是特定的生理衰老变化和合并症,这些在这些人群中出现的频率增加。无症状菌尿的高患病率和发病率几乎没有短期或长期不良后果,也没有证据表明其对生存有影响。与这个问题相关的一些重要问题尚未得到解决。首先,需要对非机构化人群进行进一步研究,以确定无症状感染的发生率及其与有症状感染的关系。在机构化人群中,需要开展研究以完善在无症状菌尿患病率如此之高的人群中发生的有症状泌尿系统感染的临床诊断。此外,应优先进一步评估老年机构化受试者中无症状菌尿储存库作为机构化人群中抗菌药物耐药性问题促成因素的影响。