Dembry L M, Andriole V T
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Infect Dis Clin North Am. 1997 Sep;11(3):663-80. doi: 10.1016/s0891-5520(05)70379-2.
Our knowledge of the spectrum of renal abscesses has evolved as a result of more sensitive radiologic techniques. The classification of intrarenal abscesses currently includes acute focal bacterial nephritis, acute multifocal bacterial nephritis, renal cortical abscess, renal corticomedullary abscess, and xanthogranulomatous pyelonephritis. The clinical presentation of these entities does not differentiate them, however, and various radiographic studies are helpful in making the diagnosis. The intrarenal abscess is usually treated successfully with antibiotic therapy alone. Antistaphylococcal therapy is indicated for the renal cortical abscess, whereas therapy directed against the common gram-negative uropathogens is indicated for most of the other entities. The perinephric abscess is often an elusive diagnosis, has a more serious prognosis, and is more difficult to treat. Drainage of the abscess and sometimes partial or complete nephrectomy, in addition to antibiotic therapy, are required for resolution.
由于采用了更敏感的放射学技术,我们对肾脓肿谱系的认识已经有所发展。目前肾内脓肿的分类包括急性局灶性细菌性肾炎、急性多灶性细菌性肾炎、肾皮质脓肿、肾皮质髓质脓肿和黄色肉芽肿性肾盂肾炎。然而,这些疾病的临床表现并不能将它们区分开来,各种影像学检查有助于做出诊断。肾内脓肿通常仅用抗生素治疗就能成功治愈。肾皮质脓肿需采用抗葡萄球菌治疗,而针对大多数其他疾病则需采用针对常见革兰氏阴性尿路病原体的治疗方法。肾周脓肿的诊断往往难以捉摸,预后更严重,治疗也更困难。除抗生素治疗外,脓肿引流以及有时进行部分或全肾切除术对于脓肿的消退是必要的。