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[微创冠状动脉旁路移植术;格罗宁根大学医院的首次临床经验]

[Minimally invasive coronary bypass grafting; first clinical experience in Groningen University Hospital].

作者信息

Breeuwsma H A, Boonstra P W, Grandjean J G, Mariani M A

机构信息

Academisch Ziekenhuis, Thoraxcentrum, Groningen.

出版信息

Ned Tijdschr Geneeskd. 1997 Jun 7;141(23):1145-8.

PMID:9380145
Abstract

OBJECTIVE

To evaluate the feasibility of minimally invasive coronary artery bypass grafting (mini-CABG) and the clinical results of the first 70 consecutive patients who underwent mini-CABG.

DESIGN

Retrospective.

SETTING

Thorax centre of Groningen University Hospital, the Netherlands.

METHODS

Seventy patients with angina pectoris and electro-cardiographically objectivated ischaemia, due to proximal stenosis of the left anterior descending coronary artery (LAD) or of the right coronary artery (RCA) were included in the study. Inclusion criteria were characteristics of the stenosis implying increased risk for morbidity and mortality at PTCA and a second coronary operation in patients who had a stenosed vein graft to the LAD. Through a small anterolateral thoracotomy (8-10 cm) in the 4th or 5th intercostal space the left internal mammary artery (LIMA) was harvested. The LIMA-to-LAD anastomosis was performed on the beating heart without cardiopulmonary bypass, by means of devices which provided temporary stabilization and occlusion of the LAD. Data of the period of hospital stay were gathered by using a standard form and on the period thereafter by telephone interviews with the patients, their general practitioners or cardiologists.

RESULTS

The in-hospital mortality was 2. In 4 patients perioperative myocardial infarction occurred. Conversion to conventional CABG was needed in 3 patients, and a temporary postoperative intra-aortic balloon pump in 1. Rethoracotomy for bleeding was done in 1 patient, who received blood transfusion. In the other patients mean postoperative bleeding was 310 ml (SD: 180). Complications were respiratory infection (n = 2) and atrial fibrillation (n = 10). The mean operation time was 95 min (SD: 26). The mean hospital stay was 4.5 days (SD: 1.9).

CONCLUSION

The mini-CABG is a feasible treatment for patients with high-risk stenosis of the LAD or RCA or with a diseased vein graft to the LAD with an acceptable mortality and morbidity and a short hospital stay.

摘要

目的

评估微创冠状动脉旁路移植术(mini-CABG)的可行性以及连续70例接受mini-CABG的患者的临床结果。

设计

回顾性研究。

地点

荷兰格罗宁根大学医院胸科中心。

方法

本研究纳入了70例因左前降支冠状动脉(LAD)或右冠状动脉(RCA)近端狭窄而患有心绞痛且心电图证实有缺血的患者。纳入标准为狭窄特征提示经皮冠状动脉腔内血管成形术(PTCA)时发病和死亡风险增加,以及LAD静脉移植物狭窄患者进行二次冠状动脉手术。通过在第4或第5肋间间隙做一个小的前外侧胸廓切开术(8 - 10厘米)获取左乳内动脉(LIMA)。在心脏跳动且无体外循环的情况下,借助能临时稳定和阻断LAD的装置进行LIMA与LAD的吻合。住院期间的数据通过标准表格收集,之后通过电话采访患者、他们的全科医生或心脏病专家获取后续期间的数据。

结果

住院死亡率为2例。4例患者发生围手术期心肌梗死。3例患者需要转为传统冠状动脉旁路移植术,1例患者术后需要临时主动脉内球囊反搏。1例患者因出血进行了再次开胸手术并接受了输血。其他患者术后平均出血量为310毫升(标准差:180)。并发症包括呼吸道感染(n = 2)和心房颤动(n = 10)。平均手术时间为95分钟(标准差:26)。平均住院时间为4.5天(标准差:1.9)。

结论

对于LAD或RCA高危狭窄患者或LAD有病变静脉移植物的患者,mini-CABG是一种可行的治疗方法,死亡率和发病率可接受,住院时间短。

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