Zaffaroni L, Costa P, Vinci G W
Sezione Autonoma per la Sterilità e la Patologia Osterica Ginecologica Funzionale, Ospedale Niguarda Ca' Granda, Milano.
Minerva Ginecol. 1997 Jul-Aug;49(7-8):361-4.
e efficacy and tolerability of 2.5% natural vaginal progesterone as luteal phase support in pharmacologically induced cycles has been evaluated.
On the basis of the administered therapy, the population studied was subdivided at random into four different groups. Sixty patients came to the Sterility Autonomous Department of the Niguarda Ca' Granda Hospital in Milan from November 1994 to January 1996. Both ultrasonographic and plasmatic hormonal parameters have been evaluated on a monthly basis.
The plasma progesterone levels and ultrasonographic endometrial thickness average values resulted more important in groups treated with topical progesterone; in these same groups a greater percentage of pregnancies was observed.
The results obtained demonstrated that the drug studied can be recommended as a valid luteal phase support in pharmacologically induced cycles.
已评估2.5%天然阴道孕酮作为药物诱导周期中黄体期支持的疗效和耐受性。
根据所给予的治疗方法，将研究人群随机分为四个不同组。1994年11月至1996年1月期间，60名患者前往米兰尼瓜尔达·卡格兰达医院的不育自主科室。每月对超声和血浆激素参数进行评估。
局部应用孕酮治疗的组中，血浆孕酮水平和超声子宫内膜厚度平均值更为重要；在这些相同的组中观察到更高的妊娠率。
所获得的结果表明，所研究的药物可推荐作为药物诱导周期中有效的黄体期支持药物。
