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[巴西马拉尼昂州圣路易斯岛的内脏利什曼病(黑热病):其演变与展望]

[Visceral leishmaniasis (kala-azar) on Ilha de São Luís, Maranhão. Brazil: its evolution and outlook].

作者信息

da Silva A R, Viana G M, Varonil C, Pires B, Nascimento M do D, Costa J M

机构信息

Departamento de Patologia, Centro de Ciências da Saúde, Universidade Federal do Maranhão São Luís, MA, Brasil.

出版信息

Rev Soc Bras Med Trop. 1997 Sep-Oct;30(5):359-68. doi: 10.1590/s0037-86821997000500002.

Abstract

Visceral leishmaniasis (kala-azar) was definitively an important disease of the state of Maranhão, Brasil since 1982. Since of then, many authors have been working with this topic in spite of reports. Nevertheless, the aspects of diagnosis, treatment an control of cure went through still hard worried the authors have been studying the disease, that came at São Luís Island since of the destabilization of the ecotopes of Lutzomya longipalpis, most important sandflies bites. After 1993 the constatation of cases with bad response to pentavalent antimonial (Glucantime) comes to add the other worries. This actual trial accost the disease and conclude about an existence of failures to Glucantime being important to have much vigilance in the diagnosis, treatment and control of cure of the patients.

摘要

自1982年以来,内脏利什曼病(黑热病)无疑是巴西马拉尼昂州的一种重要疾病。从那时起,尽管有相关报道,但许多作者一直在研究这个课题。然而,诊断、治疗和治愈控制方面仍然让研究该疾病的作者深感担忧,该病自长须罗蛉生态位不稳定以来出现在圣路易斯岛,长须罗蛉是最重要的沙蝇叮咬源。1993年之后,发现有病例对五价锑剂(葡糖酸锑钠)反应不佳,这又增加了其他担忧。本次实际试验涉及该疾病,并得出结论,葡糖酸锑钠存在治疗失败情况,这对于在患者的诊断、治疗和治愈控制方面保持高度警惕非常重要。

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