Samonis G, Maraki S, Christidou A, Georgiladakis A, Tselentis Y
Department of Clinical Bacteriology - Parasitology - Zoonoses and Geographical Medicine, University Hospital of Heraklion, Crete, Greece.
Eur J Epidemiol. 1997 Oct;13(7):831-6. doi: 10.1023/a:1007318003083.
Stool specimens from 3,600 diarrhoeal patients from the island of Crete, Greece, were examined for bacterial pathogens, during a three-year period (1992-1994). One or more pathogens were identified in 826 patients (22.9%), more often from children. Salmonella spp. were the most frequently isolated organisms in 13.6% of the patients, followed by Campylobacter in 4.7%, and enteropathogenic Escherichia coli (EPEC) in 3.9%. Yersinia enterocolitica was found in 0.7%, Shigella spp. in 0.7% and Aeromonas hydrophila in 0.05%. Vibrio spp. and enterohaemorragic E. coli were not identified in the stools tested. Resistance to ampicillin was observed in 36% of the Salmonella, 62% of the Shigella, and 27% of the EPEC isolates. Cotrimoxazole resistance was observed in 42% of the Shigella and 12% of the EPEC isolates, while tetracycline and the quinolones were inactive against almost half and erythromycin against 20% of the Campylobacter isolates. This is the first study investigating bacterial pathogens associated with diarrhoea on the island of Crete.
在1992年至1994年的三年期间，对来自希腊克里特岛的3600名腹泻患者的粪便样本进行了细菌病原体检测。826名患者（22.9%）检测出一种或多种病原体，儿童中更为常见。沙门氏菌属是最常分离出的病原体，在13.6%的患者中被检测到，其次是空肠弯曲菌，占4.7%，致病性大肠杆菌（EPEC）占3.9%。小肠结肠炎耶尔森菌的检出率为0.7%，志贺氏菌属为0.7%，嗜水气单胞菌为0.05%。在所检测的粪便中未发现弧菌属和肠出血性大肠杆菌。36%的沙门氏菌、62%的志贺氏菌和27%的EPEC分离株对氨苄青霉素耐药。42%的志贺氏菌和12%的EPEC分离株对复方新诺明耐药，而四环素和喹诺酮类药物对近一半的弯曲菌分离株无效，红霉素对20%的弯曲菌分离株无效。这是第一项关于克里特岛腹泻相关细菌病原体的研究。
