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垂直移位。第二部分。类风湿性颈椎病手术治疗后的结果。

Vertical translocation. Part II. Outcomes after surgical treatment of rheumatoid cervical myelopathy.

作者信息

Casey A T, Crockard H A, Stevens J

机构信息

Department of Surgical Neurology, The National Hospital for Neurology and Neurosurgery, London, United Kingdom.

出版信息

J Neurosurg. 1997 Dec;87(6):863-9. doi: 10.3171/jns.1997.87.6.0863.

Abstract

This is a prospective observational study in 116 patients with rheumatoid arthritis and vertical translocation who underwent cervical spine surgery after developing symptomatic myelopathy. These patients, whose mean age was 62 years, had suffered from rheumatoid arthritis for almost 25 years. Surgery was performed via a combination of anterior (67 transoral decompressions) and posterior approaches. Surgical morbidity was recorded in 39% of patients, with a 30-day mortality rate of 10.3%, which was largely related to poor preoperative neurological grade. Neurological improvement of at least one Ranawat class was observed in 55 patients. Univariate analysis revealed the following clinical variables to be associated with a good neurological outcome (Ranawat class): younger age and good preoperative muscle power. Significant radiological variables included the degree of vertical translocation as measured by the Redlund-Johnell method and the preoperative spinal cord area. The degree of transgression in the foramen magnum did not significantly affect neurological outcome. Neither the anterior nor the posterior atlantodens interval predicted neurological recovery. Multiple logistic regression models were constructed based on the preliminary evidence of the authors' univariate analysis and these confirmed the importance of preoperative neurological function, spinal cord area, and the degree of vertical translocation in influencing the final neurological grade.

摘要

这是一项针对116例类风湿性关节炎合并垂直移位且出现症状性脊髓病后接受颈椎手术的患者的前瞻性观察研究。这些患者平均年龄为62岁,患类风湿性关节炎近25年。手术通过前路(67例经口减压)和后路联合进行。39%的患者出现手术并发症,30天死亡率为10.3%,这在很大程度上与术前神经功能分级较差有关。55例患者观察到神经功能至少改善一个Ranawat分级。单因素分析显示,以下临床变量与良好的神经功能结果(Ranawat分级)相关:年龄较小和术前肌肉力量良好。重要的放射学变量包括用Redlund-Johnell方法测量的垂直移位程度和术前脊髓面积。枕骨大孔的侵犯程度对神经功能结果无显著影响。寰齿前间隙和寰齿后间隙均不能预测神经功能恢复。基于作者单因素分析的初步证据构建了多元逻辑回归模型,这些模型证实了术前神经功能、脊髓面积和垂直移位程度对最终神经功能分级的影响。

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