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更昔洛韦成功治疗一名患有肾上腺功能不全的晚期艾滋病患者。

Successful treatment with ganciclovir of a HIV endstage patient with adrenal insufficiency.

作者信息

Mühlhöfer A, Jung C, Gross M

机构信息

Medizinische Poliklinik, Klinikum Innenstadt, Ludwig-Maximilians-University Munich, Pettenkoferstr. 8a, Munich D-80336, Germany.

出版信息

Eur J Med Res. 1997 Nov 28;2(11):469-72.

PMID:9385116
Abstract

We report on a 31-year-old AIDS patient who presented with rapid progressive fatigue, weakness, weight loss and hyperpigmentation. Endoscopy showed an ulcerous CMV gastritis with the histological hallmarks of this disease. In addition, laboratory tests revealed the constellation of an adrenal insufficiency with low plasma levels of sodium and increased levels of potassium and ACTH. After initiation of ganciclovir treatment, the CMV gastritis healed and the electrolyte abnormalities were resolved within 2 weeks. We assume that a CMV adrenalitis was treated in a reversible stage. The literature on CMV adrenalitis is reviewed to support this conclusion.

摘要

我们报告了一名31岁的艾滋病患者,其表现为快速进展的疲劳、虚弱、体重减轻和色素沉着。内镜检查显示为溃疡性巨细胞病毒胃炎,并具有该疾病的组织学特征。此外,实验室检查显示存在肾上腺功能不全,血浆钠水平低,钾和促肾上腺皮质激素水平升高。开始使用更昔洛韦治疗后,巨细胞病毒胃炎愈合,电解质异常在2周内得到解决。我们认为巨细胞病毒性肾上腺炎在可逆阶段得到了治疗。本文回顾了关于巨细胞病毒性肾上腺炎的文献以支持这一结论。

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Successful treatment with ganciclovir of a HIV endstage patient with adrenal insufficiency.更昔洛韦成功治疗一名患有肾上腺功能不全的晚期艾滋病患者。
Eur J Med Res. 1997 Nov 28;2(11):469-72.
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Adrenal insufficiency in a patient with acquired immunodeficiency syndrome.获得性免疫缺陷综合征患者的肾上腺功能不全。
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Treatment of cytomegalovirus esophagitis in patients with acquired immune deficiency syndrome: a randomized controlled study of foscarnet versus ganciclovir. The Italian Cytomegalovirus Study Group.获得性免疫缺陷综合征患者巨细胞病毒性食管炎的治疗:膦甲酸钠与更昔洛韦的随机对照研究。意大利巨细胞病毒研究组
Am J Gastroenterol. 1998 Mar;93(3):317-22. doi: 10.1111/j.1572-0241.1998.00317.x.
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Successful treatment of CMV-induced adrenal insufficiency by ganciclovir in a patient with the acquired immunodeficiency syndrome.更昔洛韦成功治疗一名获得性免疫缺陷综合征患者的巨细胞病毒诱导的肾上腺功能不全。
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[Polyradiculopathy caused by cytomegalovirus in AIDS patients: successful treatment with highly active antiretroviral therapy (HAART)].[艾滋病患者巨细胞病毒引起的多发性神经根病:高效抗逆转录病毒疗法(HAART)成功治疗]
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Low dose adrenocorticotropic hormone test and adrenal insufficiency in critically ill acquired immunodeficiency syndrome patients.危重症获得性免疫缺陷综合征患者的低剂量促肾上腺皮质激素试验与肾上腺功能不全
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