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心血管疾病管理中种族差异的研究。

Examination of racial differences in management of cardiovascular disease.

作者信息

Ferguson J A, Tierney W M, Westmoreland G R, Mamlin L A, Segar D S, Eckert G J, Zhou X H, Martin D K, Weinberger M

机构信息

Center for Health Services Research, Roudebush Veterans Affairs Medical Center, Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA.

出版信息

J Am Coll Cardiol. 1997 Dec;30(7):1707-13. doi: 10.1016/s0735-1097(97)00365-3.

Abstract

OBJECTIVES

We sought to identify the clinical characteristics associated with, and to investigate the impact of cohort selection criteria on, interracial use of invasive cardiac procedures and to determine survival.

BACKGROUND

Although interracial differences in the use of invasive cardiac procedures have been previously reported, the underlying reasons are not known.

METHODS

A retrospective cohort study was conducted at a Veterans Affairs Medical Center. Study patients were evaluated for cardiovascular disease between January 1 and December 31, 1993.

RESULTS

The study included 1,406 male patients (85% white, 58% married), with a mean age of 63.4 years. African Americans were less likely than whites to undergo procedures (cardiac catheterization: odds ratio [OR] 0.37, 95% confidence interval [CI] 0.24 to 0.58; coronary angioplasty: OR 0.60, 95% CI 0.25 to 1.49; coronary bypass surgery: OR 0.22, 95% CI 0.08 to 0.63; any procedure: OR 0.32, 95% CI 0.21 to 0.50). On bivariate analysis, patients who underwent cardiac procedures were more likely to be younger, married and reside nonlocally and less likely to have severe comorbid disease; however, African Americans were less likely to be married and to reside nonlocally and more likely to have severe comorbid disease. Cohorts adjusting for referral status and specified cardiac diagnoses reduced or reversed interracial treatment differences. Thirty-day and 1-year survival rates (96% and 87.6%, respectively) were equivalent.

CONCLUSIONS

Racial disparity in invasive cardiac procedure use may be partially explained by clinical differences and cohort selection bias. Despite treatment differences, survival rates were equivalent in African Americans and whites.

摘要

目的

我们试图确定与侵入性心脏手术的种族间使用相关的临床特征,并研究队列选择标准对其的影响,同时确定生存率。

背景

尽管先前已报道侵入性心脏手术使用方面的种族差异,但其潜在原因尚不清楚。

方法

在一家退伍军人事务医疗中心进行了一项回顾性队列研究。对1993年1月1日至12月31日期间因心血管疾病接受评估的患者进行研究。

结果

该研究纳入了1406名男性患者(85%为白人,58%已婚),平均年龄为63.4岁。非裔美国人接受手术的可能性低于白人(心脏导管插入术:比值比[OR]0.37,95%置信区间[CI]0.24至0.58;冠状动脉血管成形术:OR 0.60,95%CI 0.25至1.49;冠状动脉搭桥手术:OR 0.22,95%CI 0.08至0.63;任何手术:OR 0.32,95%CI 0.21至0.50)。在双变量分析中,接受心脏手术的患者更可能年轻、已婚且居住在外地,且患严重合并症的可能性较小;然而,非裔美国人结婚和居住在外地的可能性较小,且患严重合并症的可能性较大。调整转诊状态和特定心脏诊断的队列减少或扭转了种族间的治疗差异。30天和1年生存率(分别为96%和87.6%)相当。

结论

侵入性心脏手术使用方面的种族差异可能部分由临床差异和队列选择偏倚解释。尽管存在治疗差异,但非裔美国人和白人的生存率相当。

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