Hanumanthu S, Butler J, Chomsky D, Davis S, Wilson J R
Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tenn 37232-6300, USA.
Circulation. 1997 Nov 4;96(9):2842-8. doi: 10.1161/01.cir.96.9.2842.
Most patients with heart failure are currently managed by physicians with little specific expertise in heart failure. This management system has been associated with evidence of suboptimal care, such as high rates of hospital readmission and underuse of ACE inhibitors. The current study was undertaken to determine whether hospitalization rates and functional outcomes are improved when patients are managed by physicians with special expertise in heart failure working in a dedicated heart failure program.
All patients with heart failure referred to the Vanderbilt Heart Failure and Heart Transplantation Program between July 1994 and June 1995 were identified. Annual hospitalization rates, medications, and peak exercise capacity before and after referral were compared in patients followed for >30 days. A total of 187 patients were referred during the index time period, of whom 134 (72%) were followed for >30 days. During the year before referral, 94% of the patients were hospitalized (210 cardiovascular hospitalizations) versus 44% of the patients during the year after referral (104 hospitalizations) (53% reduction) (P<.01). Hospitalizations for heart failure decreased from 164 to 60 for all patients regardless of follow-up duration and decreased from 97 to 30 (69% reduction) for patients followed at least 1 year after referral. Eighty-eight of the patients were able to exercise at the time of referral. Peak exercise VO2 in this group increased from 12.8+/-4.7 to 15.7+/-4.8 mL x min(-1) x kg(-1) (P<.01) by 6 months after referral. Loop diuretic doses were on averaged doubled during the first 6 months after referral.
These findings suggest that patients with heart failure have fewer hospitalizations for heart failure and are significantly more functional when managed by heart failure specialists working in a dedicated heart failure program rather than by physicians with limited expertise in heart failure.
目前大多数心力衰竭患者由对心力衰竭缺乏专业特长的医生进行管理。这种管理系统已被证明存在护理欠佳的情况,如高再住院率和血管紧张素转换酶抑制剂使用不足。当前研究旨在确定由在专门的心力衰竭项目中工作的具有心力衰竭专业特长的医生管理患者时,住院率和功能结局是否会得到改善。
确定了1994年7月至1995年6月期间转诊至范德比尔特心力衰竭与心脏移植项目的所有心力衰竭患者。对随访超过30天的患者转诊前后的年住院率、用药情况和峰值运动能力进行了比较。在索引时间段内共转诊了187例患者,其中134例(72%)随访超过30天。转诊前一年,94%的患者住院(210次心血管住院),而转诊后一年为44%的患者(104次住院)(降低了53%)(P<0.01)。无论随访时间长短,所有患者因心力衰竭的住院次数从164次降至60次,转诊后至少随访1年的患者从97次降至30次(降低了69%)。88例患者在转诊时能够运动。该组患者转诊后6个月时的峰值运动耗氧量从12.8±4.7增加至15.7±4.8 ml·min⁻¹·kg⁻¹(P<0.01)。转诊后的前6个月内,襻利尿剂剂量平均增加了一倍。
这些发现表明,与由心力衰竭专业知识有限的医生管理相比,由在专门的心力衰竭项目中工作的心力衰竭专科医生管理心力衰竭患者时,因心力衰竭的住院次数更少,且功能明显更好。