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Inositol 1,3,4,5-tetrakisphosphate and Ca2+ homoeostasis: the role of GAP1IP4BP.

作者信息

Cullen P J, Loomis-Husselbee J, Dawson A P, Irvine R F

机构信息

Department of Biochemistry, University of Bristol, School of Medical Sciences, U.K.

出版信息

Biochem Soc Trans. 1997 Aug;25(3):991-6. doi: 10.1042/bst0250991.

DOI:10.1042/bst0250991
PMID:9388588
Abstract
摘要

相似文献

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2
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Nuclear transport: randy couples.
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引用本文的文献

1
The regulation and function of inositol 1,4,5-trisphosphate 3-kinases.肌醇1,4,5-三磷酸3-激酶的调节与功能
Adv Enzyme Regul. 2006;46(1):314-23. doi: 10.1016/j.advenzreg.2006.01.009. Epub 2006 Jul 20.
2
The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells.人肌醇-1,4,5-三磷酸3-激酶的三种同工酶在COS-7细胞中转染时显示出特定的细胞内定位,但对Ca2+的反应相当。
Biochem J. 2003 Aug 15;374(Pt 1):41-9. doi: 10.1042/BJ20021963.
3
Antisense knock out of the inositol 1,3,4,5-tetrakisphosphate receptor GAP1(IP4BP) in the human erythroleukemia cell line leads to the appearance of intermediate conductance K(Ca) channels that hyperpolarize the membrane and enhance calcium influx.
在人红白血病细胞系中,通过反义技术敲除肌醇1,3,4,5 - 四磷酸受体GAP1(IP4BP)会导致出现中间电导的钾钙通道,这些通道使细胞膜超极化并增强钙内流。
J Gen Physiol. 1999 Jan;113(1):81-96. doi: 10.1085/jgp.113.1.81.
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The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation.含Src同源2结构域的肌醇磷酸酶(SHIP)是肥大细胞脱颗粒的守门人。
Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11330-5. doi: 10.1073/pnas.95.19.11330.
5
Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by ins(1,3,4, 5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor.肌醇(1,3,4,5)四磷酸对肌醇(2,4,5)三磷酸刺激的钙离子动员的调节作用:被激活的G蛋白增强作用,以及一种GAP1蛋白(一种假定的肌醇(1,3,4,5)四磷酸受体)参与的证据。
Biochem J. 1998 May 1;331 ( Pt 3)(Pt 3):947-52. doi: 10.1042/bj3310947.