汉防己甲素对人癌细胞阿霉素或长春新碱耐药性的体外逆转作用
[Reversal of adriamycin or vincristine resistance by tetrandrine in human cancer cells in vitro].
作者信息
Ye Z, Sun A, Li L, Cao X, Ye W
机构信息
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.
出版信息
Zhongguo Zhong Yao Za Zhi. 1996 Jun;21(6):369-71, 384.
PMID:9388928
Abstract
In an in vitro culture system of human cancer cells MCF-7 and its adriamycin-resistant line MCF-7/Ad or KB and its vincristine-resistant line KBv200, tetrandrine was found to exhibit significantly selective anticancer activity against the drug-resistant cancer cell MCF-7/Ad. In addition, essentially complete reversal effects of tetrandrine on drug resistance were observed in MCF/Ad or KBv200.
摘要
在人癌细胞MCF-7及其阿霉素耐药株MCF-7/Ad或KB及其长春新碱耐药株KBv200的体外培养系统中，发现粉防己碱对耐药癌细胞MCF-7/Ad具有显著的选择性抗癌活性。此外，在MCF/Ad或KBv200中观察到粉防己碱对耐药性具有基本完全的逆转作用。
Zotero 插件