Uribe M, Schalm S W, Summerskill W H, Go V L
Gastroenterology. 1976 Aug;71(2):362-4.
After prednisone (two 5 mg tablets) was given to each of six normal volunteers with water or with a liquid meal, standard pharmacokinetic parameters of prednisolone metabolism were similar, except that peak serum prednisolone concentrations occurred later after the meal. We conclude that prednisone can be given with a meal without significantly affecting the metabolism of prednisone or prednisolone.
给六名正常志愿者每人服用泼尼松（两片5毫克片剂），分别用水或流食送服，结果除了饭后血清泼尼松龙浓度峰值出现时间较晚外，泼尼松龙代谢的标准药代动力学参数相似。我们得出结论，泼尼松可以与食物一起服用，而不会显著影响泼尼松或泼尼松龙的代谢。
