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必需脂肪酸制剂治疗胎儿生长受限的效果

The effects of essential fatty acids preparation in the treatment of intrauterine growth retardation.

作者信息

Zhang L

机构信息

Department of Obstetrics and Gynecology, Xiangya Hospital, Human Medical University, Changsha, China.

出版信息

Am J Perinatol. 1997 Oct;14(9):535-7. doi: 10.1055/s-2007-994329.

DOI:10.1055/s-2007-994329
PMID:9394162
Abstract

A treatment of intravenous infusion of glucose, amino acids, and emulsion enriched in essential fatty acids (EFAs), linoleic, and linolenic acids were given to 30 pregnant women with intrauterine growth retardation (IUGR) and 28 non-EFAs treated cases as controls. There was a marked gain in fetal biparietal diameter (BPD) and in the estimated weight of the treated group over the control group. The mean birth weight was significantly different in the two groups. Fetal BPD increased much more in patients treated with EFAs at 28-34 gestational weeks than those at 34 1/7-37 weeks, which indicates that early initiate complement of n-3 and n-6 fatty acids to IUGR mothers may correct pregnancy-induced EFAs deficiency and maternal-fetal malnutrition, which demonstrates a fetal catch-up of growth in the brain and the whole body.

摘要

对30例宫内生长受限(IUGR)孕妇进行静脉输注葡萄糖、氨基酸和富含必需脂肪酸(EFA)、亚油酸和亚麻酸的乳剂的治疗,并将28例未接受EFA治疗的病例作为对照。与对照组相比,治疗组胎儿双顶径(BPD)和估计体重有显著增加。两组的平均出生体重有显著差异。在孕28 - 34周接受EFA治疗的患者中,胎儿BPD的增加幅度比孕34 1/7 - 37周接受治疗的患者大得多,这表明早期对IUGR母亲补充n - 3和n - 6脂肪酸可能纠正孕期EFA缺乏和母婴营养不良,这表现为胎儿在大脑和全身的生长追赶。

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