Schechtman K B, Kutner N G, Wallace R B, Buchner D M, Ory M G
Washington University School of Medicine, Division of Biostatistics, St. Louis, MO 63110, USA.
J Psychosom Res. 1997 Nov;43(5):513-27. doi: 10.1016/s0022-3999(97)00117-7.
The purposes of this report are: (1) to investigate the association between sleep disturbances and depressive symptomatology in older adults; (2) to evaluate the degree to which gender serves to mediate this relationship; and (3) to determine whether several predefined covariates help to explain the association between sleep disturbance and depressive symptoms. This is a retrospective and cross-sectional analysis of baseline data from 485 elderly adults enrolled in three of the eight clinical sites participating in the Frailty and Injuries: Cooperative Studies of Intervention Techniques (FICSIT) trials. FICSIT was a linked series of randomized clinical trials which evaluated the impact of various exercise interventions on several measures of frailty in older adults. Women reported more depressive symptoms and more sleep disturbances than men. Sleep disturbances were independently associated with depressive symptoms, bodily pain, a history of falling, limited education, being married, and being female. Gender interactions suggest that, although women reported more depressive symptoms and more chronic health conditions than men, both may be more important predictors of sleep disturbance in men. By contrast, being married may be more predictive in women. Finally, the data suggest a stronger relationship between sleep disturbance and depressive symptoms in men than in women.
(1)调查老年人睡眠障碍与抑郁症状之间的关联;(2)评估性别在多大程度上介导这种关系;(3)确定几个预先定义的协变量是否有助于解释睡眠障碍与抑郁症状之间的关联。这是一项对参与衰弱与损伤:干预技术合作研究(FICSIT)试验的八个临床站点中的三个站点招募的485名老年人的基线数据进行的回顾性横断面分析。FICSIT是一系列相关的随机临床试验,评估了各种运动干预对老年人衰弱的几种测量指标的影响。女性比男性报告了更多的抑郁症状和更多的睡眠障碍。睡眠障碍与抑郁症状、身体疼痛、跌倒史、教育程度有限、已婚以及女性性别独立相关。性别交互作用表明,尽管女性比男性报告了更多的抑郁症状和更多的慢性健康状况,但两者可能都是男性睡眠障碍更重要的预测因素。相比之下,已婚对女性可能更具预测性。最后,数据表明男性睡眠障碍与抑郁症状之间的关系比女性更强。