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巴西副球孢子菌抗血清中抗 gp43 抗体与洛博病皮肤病变提取物的反应性。初步报告。

Reactivity of anti-gp43 antibodies from Paracoccidioides brasiliensis antiserum with extracts from cutaneous lesions of Lobo's disease. Preliminary note.

作者信息

Vidal M S, Palacios S A, de Melo N T, Lacaz C da S

机构信息

Instituto de Medicina Tropical de São Paulo, Brasil.

出版信息

Rev Inst Med Trop Sao Paulo. 1997 Jan-Feb;39(1):35-7. doi: 10.1590/s0036-46651997000100007.

Abstract

We demonstrated through several immunochemical tests the presence of gp43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease. This glicoprotein is one of the immunodominant antigens in this species, and is used to identify it. The demonstration of gp43 tissues infected by the agent of Jorge Lobo's disease is an additional evidence for classifying it in the genera Paracoccidioides, species loboi.

摘要

我们通过多项免疫化学检测,证实了在雅氏芽生菌病皮肤病变提取物中存在巴西副球孢子菌的gp43。这种糖蛋白是该菌种的主要免疫显性抗原之一,可用于对其进行鉴定。在雅氏芽生菌病病原体感染的组织中证实存在gp43,是将其归类于副球孢子菌属、洛博伊种的又一证据。

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