Engelhart D A, Lavins E S, Seligman S S, Sutheimer C A
Cuyahoga County Coroner's Office, Cleveland, Ohio 44106, USA.
J Anal Toxicol. 1997 Nov-Dec;21(7):576-9. doi: 10.1093/jat/21.7.576.
A 78-year-old woman was found dead in her basement. Qualitative screening of available postmortem specimens detected the presence of diltiazem and pentoxifylline. Quantitations were carried out by gas chromatography using nitrogen-phosphorus detection and confirmed by gas chromatography-mass spectrometry with the following results: blood, 0.59 mg/dL diltiazem and 0.63 mg/dL pentoxifylline; urine, 1.17 mg/dL diltiazem and 0.08 mg/dL pentoxifylline; bile, 0.40 mg/dL diltiazem and 0.22 mg/dL pentoxifylline; gastric contents, 0.28 mg/dL diltiazem and 0.02 mg/dL pentoxifylline. Both drugs were found qualitatively in formaline-fixed tissues.
一名78岁女性被发现死于自家地下室。对可获取的尸检样本进行定性筛查，检测到存在地尔硫䓬和己酮可可碱。采用氮磷检测的气相色谱法进行定量分析，并通过气相色谱-质谱联用进行确认，结果如下：血液中，地尔硫䓬为0.59mg/dL，己酮可可碱为0.63mg/dL；尿液中，地尔硫䓬为1.17mg/dL，己酮可可碱为0.08mg/dL；胆汁中，地尔硫䓬为0.40mg/dL，己酮可可碱为0.22mg/dL；胃内容物中，地尔硫䓬为0.28mg/dL，己酮可可碱为0.02mg/dL。在福尔马林固定组织中定性检测到了这两种药物。
