Brown J W
Department of Microbiology, North Carolina State University, Raleigh, NC 27695, USA.
Nucleic Acids Res. 1998 Jan 1;26(1):351-2. doi: 10.1093/nar/26.1.351.
Ribonuclease P is responsible for the 5'-maturation of tRNA precursors. Ribonuclease P is a ribonucleoprotein, and in bacteria the RNA subunit alone is catalytically active in vitro , i.e., it is a ribozyme. The Ribonuclease P Database is a compilation of ribonuclease P sequences, sequence alignments, secondary structures, three-dimensional models, and accessory information, available via the World Wide Web (http: //www.mbio.ncsu.edu/RNaseP/home.html ).
核糖核酸酶P负责tRNA前体的5'端成熟。核糖核酸酶P是一种核糖核蛋白,在细菌中,单独的RNA亚基在体外具有催化活性,即它是一种核酶。核糖核酸酶P数据库收集了核糖核酸酶P的序列、序列比对、二级结构、三维模型及辅助信息,可通过万维网(http://www.mbio.ncsu.edu/RNaseP/home.html )获取。