Klingler H C, Madersbacher S, Djavan B, Schatzl G, Marberger M, Schmidbauer C P
Department of Urology, University of Vienna, Austria.
J Urol. 1998 Jan;159(1):191-4. doi: 10.1016/s0022-5347(01)64054-0.
The aim of this prospective study was to determine morbidity and complication rate of invasive urodynamic evaluation of the lower urinary tract after transurethral multichannel pressure-flow studies.
The study included 63 men with the clinical diagnosis of benign prostatic hyperplasia and 56 women with stress urinary incontinence. All patients underwent routine pressure-flow study as part of the urodynamic evaluation. A week later the patients returned for followup which also included a detailed interview on post-evaluation morbidity.
The overall complication rate, including urinary retention, gross hematuria, urinary tract infection and fever, was 19.0% (12 of 63) for men and 1.8% (1 of 56) for women. In men there was no statistically significant correlation between post-void residual urine or age and complication rate (p > 0.05). Of the men 4.8% experienced post-investigational urinary retention and all of them had significant bladder outflow obstruction. In addition, obstructed men reported a higher incidence of dysuria and pain (76.2%, 32 of 42) compared to those without obstruction (57.1%, 12 of 21), whereas only 53.6% of women reported these complaints. Of the 63 men 4 (6.2%) had significant urinary tract infections, while only 1 woman (1.8%) had infections.
Invasive urodynamic investigation is associated with a considerable rate of complications and morbidity, particularly in men with infravesical obstruction. These facts must be considered and discussed with the patient before urodynamic testing.
这项前瞻性研究的目的是确定经尿道多通道压力-流率研究后下尿路侵入性尿动力学评估的发病率和并发症发生率。
该研究纳入了63例临床诊断为良性前列腺增生的男性和56例压力性尿失禁的女性。所有患者均接受了作为尿动力学评估一部分的常规压力-流率研究。一周后，患者返回进行随访，其中还包括对评估后发病率的详细访谈。
总体并发症发生率，包括尿潴留、肉眼血尿、尿路感染和发热，男性为19.0%（63例中的12例），女性为1.8%（56例中的1例）。在男性中，排尿后残余尿量或年龄与并发症发生率之间无统计学显著相关性（p>0.05）。4.8%的男性经历了检查后尿潴留，且他们均有明显的膀胱流出道梗阻。此外，与无梗阻的男性（57.1%，21例中的12例）相比，梗阻性男性尿痛和疼痛的发生率更高（76.2%，42例中的32例），而只有53.6%的女性有这些主诉。63例男性中有4例（6.2%）发生了严重尿路感染，而只有1例女性（1.8%）发生感染。
侵入性尿动力学检查与相当高的并发症和发病率相关，尤其是在膀胱下梗阻的男性中。在进行尿动力学检查之前，必须将这些情况告知患者并与他们讨论。
