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运动训练对降低血压的有效性:为期4周或更长时间的随机对照试验的荟萃分析

The effectiveness of exercise training in lowering blood pressure: a meta-analysis of randomised controlled trials of 4 weeks or longer.

作者信息

Halbert J A, Silagy C A, Finucane P, Withers R T, Hamdorf P A, Andrews G R

机构信息

Department of General Practice, Flinders University of South Australia, Bedford Park.

出版信息

J Hum Hypertens. 1997 Oct;11(10):641-9. doi: 10.1038/sj.jhh.1000509.

DOI:10.1038/sj.jhh.1000509
PMID:9400906
Abstract

OBJECTIVE

To identify the features of an optimal exercise programme in terms of type of exercise, intensity and frequency that would maximise the training induced decrease in blood pressure (BP).

DATA IDENTIFICATION

Trials were identified by a systematic search of Medline, Embase and Science Citation Index (SCI), previous review articles and the references of relevant trials, from 1980 until 1996, including only English language studies.

STUDY SELECTION

The inclusion criteria were limited to randomised controlled trials of aerobic or resistance exercise training conducted over a minimum of 4 weeks where systolic and diastolic BP was measured.

RESULTS

A total of 29 studies (1533 hypertensive and normotensive participants) were included, 26 used aerobic exercise training, two trials used resistance training and one study had both resistance and aerobic training groups. Aerobic exercise training reduced systolic BP by 4.7 mm Hg (95% CI: 4.4, 5.0) and diastolic BP by 3.1 mm Hg (95% CI: 3.0, 3.3) as compared to a non-exercising control group, however, significant heterogeneity was observed between trials in the analysis. The BP reduction seen with aerobic exercise training was independent of the intensity of exercise and the number of exercise sessions per week. The evidence for the effect of resistance exercise training was inconclusive.

CONCLUSIONS

Aerobic exercise training had a small but clinically significant effect in reducing systolic and diastolic BP. Increasing exercise intensity above 70% VO2 max or increasing exercise frequency to more than three sessions per week did not have any additional impact on reducing BP.

摘要

目的

确定最佳运动方案在运动类型、强度和频率方面的特征,以使训练引起的血压(BP)下降最大化。

数据识别

通过系统检索1980年至1996年的医学索引(Medline)、荷兰医学文摘数据库(Embase)和科学引文索引(SCI)、先前的综述文章以及相关试验的参考文献来识别试验,仅包括英语研究。

研究选择

纳入标准仅限于至少进行4周的有氧或抗阻运动训练的随机对照试验,其中测量收缩压和舒张压。

结果

共纳入29项研究(1533名高血压和血压正常参与者),26项使用有氧运动训练,2项试验使用抗阻训练,1项研究有抗阻训练组和有氧运动训练组。与非运动对照组相比,有氧运动训练使收缩压降低4.7 mmHg(95%CI:4.4,5.0),舒张压降低3.1 mmHg(95%CI:3.0,3.3),然而,分析中各试验间观察到显著异质性。有氧运动训练导致的血压降低与运动强度和每周运动次数无关。抗阻运动训练效果的证据尚无定论。

结论

有氧运动训练在降低收缩压和舒张压方面有小但具有临床意义的效果。将运动强度增加到高于最大摄氧量的70%或每周运动频率增加到超过三次对降低血压没有额外影响。

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