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职业及疟疾既往史在经典型卡波西肉瘤病因学中的作用:撒丁岛东北部的一项病例对照研究

The role of occupation and a past history of malaria in the etiology of classic Kaposi's sarcoma: a case-control study in north-east Sardinia.

作者信息

Cottoni F, Masala M V, Budroni M, Rosella M, Satta R, Locatelli F, Montesu M A, De Marco R

机构信息

Istituto di Dermatologia, Università di Sassari, Italy.

出版信息

Br J Cancer. 1997;76(11):1518-20. doi: 10.1038/bjc.1997.587.

DOI:10.1038/bjc.1997.587
PMID:9400951
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2228163/
Abstract

A case-control study was performed to determine the role of rural factors including occupation and previous malaria exposure in the development of classic Kaposi's sarcoma (CKS) in a high incidence area of Europe. The occurrence of CKS association with other malignancies was also examined. The results showed that the risk of having CKS was significantly increased in subjects farming cereals, while a previous history of malaria did not influence the risk of developing CKS. A near-significant increase in associated tumours was found.

摘要

在欧洲一个高发病率地区开展了一项病例对照研究,以确定包括职业和既往疟疾暴露在内的农村因素在经典卡波西肉瘤(CKS)发病中的作用。同时还研究了CKS与其他恶性肿瘤的关联情况。结果显示,种植谷物的受试者患CKS的风险显著增加,而既往疟疾史并不影响患CKS的风险。研究发现相关肿瘤有近乎显著的增加。

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本文引用的文献

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KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma.患有和未患卡波西肉瘤的美国人、意大利人和乌干达人中的卡波西肉瘤相关疱疹病毒抗体
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Br J Cancer. 1996 May;73(9):1132-3. doi: 10.1038/bjc.1996.217.
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Epidemiology of Kaposi's sarcoma in Sweden prior to the acquired immunodeficiency syndrome.获得性免疫缺陷综合征之前瑞典卡波西肉瘤的流行病学。
Int J Cancer. 1988 Sep 15;42(3):346-51. doi: 10.1002/ijc.2910420307.
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The distribution of non-Burkitt, non-Hodgkin's lymphomas in Uganda in relation to malarial endemicity.
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