Altomare D F, Rinaldi M, Pannarale O C, Memeo V
Coloproctology Unit, University of Bari Medical School, Italy.
Int J Colorectal Dis. 1997;12(5):308-12. doi: 10.1007/s003840050112.
The possibility of converting an easily fatiguable muscle like the gracilis muscle into a fatigue-resistant one using chronic electrostimulation has renewed interest in Pickrell's procedure. Between July 1991 and June 1996, 9 patients (2 M; 7 F) mean age = 45 y (range 14-72) underwent dynamic graciloplasty using Medtronic electrostimulators. Five patients had faecal incontinence (2 congenitally anomaly, 1 neurological, 2 post-operative) and 4 had a perineal colostomy performed either simultaneously (two cases) or at 3 to 4 years after abdominoperineal excision of the rectum. Early post-operative complications included distal tendon necrosis [1], perineal colostomy breakdown [1], detachment of the gracilis tendon [2] and seroma in the thigh [1]. Long-term complications included rectocele with faecal impaction in one patient with imperforate anus, anal stricture in one patient who had refashioning of a perineal colostomy, and displacement of the lead from the main nerve in 3 with external expulsion in 2. The patient with anal stricture was successfully treated with anoplasty but subsequently returned to an abdominal colostomy due to stricture recurrence 2 years later. The rectocele was successfully treated using a transvaginal approach. Electrical conversion of the muscle was completed in all patients but long term functional results are available for only 5 cases. Manometry revealed a significant improvement in anal pressure under electro-stimulation and the continence grading scale score significantly improved in 4 patients. The technique is applicable to a very selected group of patients with no other options but is still in the experimental phase and should not be performed outside controlled trials. Repeated hospitalisation and reoperations are often required although the complication rate may diminish and improve with experience.
利用慢性电刺激将像股薄肌这样容易疲劳的肌肉转变为抗疲劳肌肉的可能性,重新引发了人们对皮克雷尔手术的兴趣。在1991年7月至1996年6月期间,9例患者(2例男性;7例女性),平均年龄45岁(范围14 - 72岁),使用美敦力电刺激器接受了动态股薄肌成形术。5例患者有大便失禁(2例先天性异常,1例神经源性,2例术后),4例患者在直肠腹会阴切除术后同时(2例)或3至4年后进行了会阴结肠造口术。术后早期并发症包括远端肌腱坏死[1例]、会阴结肠造口破裂[1例]、股薄肌腱断裂[2例]和大腿血清肿[1例]。长期并发症包括1例肛门闭锁患者出现直肠膨出伴粪便嵌塞,1例进行会阴结肠造口重塑的患者出现肛门狭窄,3例患者导线从主神经移位,其中2例出现外部排出。肛门狭窄患者经肛门成形术成功治疗,但2年后因狭窄复发再次行腹部结肠造口术。直肠膨出经阴道途径成功治疗。所有患者均完成了肌肉的电转换,但仅5例有长期功能结果。测压显示电刺激下肛门压力有显著改善,4例患者的控便分级量表评分显著提高。该技术适用于极少数没有其他选择的患者群体,但仍处于实验阶段,不应在对照试验之外进行。尽管随着经验积累并发症发生率可能降低和改善,但通常仍需要反复住院和再次手术。