Simon J A, Ricci J L, Di Cesare P E
Department of Orthopedic Surgery, Hospital for Joint Diseases Orthopedic Institute, New York, New York, USA.
Am J Orthop (Belle Mead NJ). 1997 Nov;26(11):754-62.
Bioresorbable materials overcome two major disadvantages of the metal alloys most commonly used in fracture-fixation devices: their extreme stiffness, which causes stress shielding of the underlying bone, and the necessity, in a significant number of cases, of removing metallic implants after fracture healing is complete. The orthopedic surgeon now has the use of polylactic acid, polyglycolic acid, and polydioxanone implants for the fixation of small cancellous bone fractures. The currently available bioresorbable materials lack strength and stiffness and are associated with inflammatory reactions and osteolysis in a significant number of cases. Surgeons should use the available pins and screws with extreme care and attention to the characteristics of each individual injury, particularly its healing characteristics, as well as to the material's initial mechanical properties, degradation rates, and associated complications.
其极高的刚度会导致下方骨骼的应力遮挡，以及在大量情况下骨折愈合完成后需要取出金属植入物。骨科医生现在可以使用聚乳酸、聚乙醇酸和聚二氧杂环己酮植入物来固定小的松质骨骨折。目前可用的生物可吸收材料缺乏强度和刚度，并且在大量情况下会引发炎症反应和骨溶解。外科医生应极其小心地使用现有的钢针和螺钉，并关注每个个体损伤的特征，特别是其愈合特征，以及材料的初始力学性能、降解率和相关并发症。
