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脑脊液分流术在患有获得性免疫缺陷综合征并伴有隐球菌性脑膜炎及无法控制的颅内高压患者中的应用。

Use of cerebrospinal fluid shunts in patients having acquired immunodeficiency syndrome with cryptococcal meningitis and uncontrollable intracranial hypertension.

作者信息

Bach M C, Tally P W, Godofsky E W

机构信息

Department of Medicine, Manatee Memorial Hospital, Bradenton, Florida, USA.

出版信息

Neurosurgery. 1997 Dec;41(6):1280-2; discussion 1282-3. doi: 10.1097/00006123-199712000-00008.

Abstract

OBJECTIVE

To evaluate the treatment of serious and uncontrollable intracranial hypertension in patients with acquired immunodeficiency syndrome who developed cryptococcal meningitis.

METHODS

All cases of cryptococcal meningitis with elevated pressure and acquired immunodeficiency syndrome were reviewed in detail and described.

RESULTS

Cerebrospinal fluid shunting dramatically improved these critically ill patients and was much more successful than serial lumbar punctures or the use of high-dose dexamethasone.

CONCLUSION

Patients with acquired immunodeficiency syndrome who develop cryptococcal meningitis and who suffer serious visual loss or ocular palsies with elevated pressures should be considered for cerebrospinal fluid shunting at an early stage.

摘要

目的

评估获得性免疫缺陷综合征患者发生隐球菌性脑膜炎时严重且难以控制的颅内高压的治疗方法。

方法

详细回顾并描述了所有伴有压力升高的隐球菌性脑膜炎及获得性免疫缺陷综合征病例。

结果

脑脊液分流术显著改善了这些重症患者的状况,比连续腰椎穿刺或使用大剂量地塞米松更为成功。

结论

发生隐球菌性脑膜炎且伴有严重视力丧失或眼压升高导致眼肌麻痹的获得性免疫缺陷综合征患者,应在早期考虑进行脑脊液分流术。

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